PDF DatasheetDog Caveolin-1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Caveolin-1 based upon sequence from: Dog
Host: QP9031 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Canis lupus familiaris (Dog) (Canis familiaris) Caveolin-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9031.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Thr17
Amino Acid Sequence: MSGGKYVDSE GHLYTVPIRE QGNIYKPNNK AMAEEMSEKQ VYDAHTKEID LVNRDPKHLN DDVVKIDFED VIAEPEGTHS FDGIWKASFT TFTVTKYWFY RLLSALFGIP MALIWGIYFA ILSFLHIWAV VPCIKSFLIE IQCISRVYSI YVHTFCDPFF EAVGKIFSNI RINMQKET
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Dog Caveolin-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Canine Caveolin-1 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CAV1 |
| Entrez Gene ID | 403980 |
| Ensemble Gene ID | ENSCAFG00000003404 |
| RefSeq Protein Accession(s) | NP_001003296.1 |
| RefSeq mRNA Accession(s) | NM_001003296.1, XM_005628347.2, XM_014118875.1 |
| UniProt ID(s) | P33724 |
| UniGene ID(s) | Cfa.3850 |
| COSMIC ID Link(s) | CAV1 |
| KEGG Gene ID(s) | cfa:403980 |
| General Description of Recombinant Canine Caveolin-1 Protein. | |
| Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. May act as a scaffolding protein within caveolar mbranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Recruits CTNNB1 to caveolar mbranes and may regulate CTNNB1-mediated signaling through the Wnt pathway. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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