PDF DatasheetMouse Histone H3-like centromeric protein A Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Histone H3-like centromeric protein A based upon sequence from: Mouse
Host: QP9060 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Histone H3-like centromeric protein A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9060.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Pro134
Amino Acid Sequence: MGPRRKPQTP RRRPSSPAPG PSRQSSSVGS QTLRRRQKFM WLKEIKTLQK STDLLFRKKP FSMVVREICE KFSRGVDFWW QAQALLALQE AAEAFLIHLF EDAYLLSLHA GRVTLFPKDI QLTRRIRGFE GGLP
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse Histone H3-like centromeric protein A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse Histone H3-like centromeric protein A Protein General Information | |
|---|---|
| Alternate Names | |
| Cenp-A | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Cenpa |
| Entrez Gene ID | 12615 |
| Ensemble Gene ID | ENSMUSG00000029177 |
| RefSeq Protein Accession(s) | NP_001289058.1 |
| RefSeq mRNA Accession(s) | NM_001302129.1, NM_001302130.1, NM_001302131.1, NM_001302132.1, NM_007681.3 |
| UniProt ID(s) | O35216 |
| UniGene ID(s) | Mm.290563 |
| COSMIC ID Link(s) | Cenpa |
| KEGG Gene ID(s) | mmu:12615 |
| General Description of Recombinant Mouse Histone H3-like centromeric protein A Protein. | |
| Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assbly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro) . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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