PDF DatasheetHuman Muscarinic acetylcholine receptor M3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Muscarinic acetylcholine receptor M3 based upon sequence from: Human
Host: QP9067 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Muscarinic acetylcholine receptor M3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9067.
Bioactivity Data: Untested
Full Length? Cytoplasmic Domain
Expression Region: Arg253 – Thr492
Amino Acid Sequence: RIYKETEKRT KELAGLQASG TEAETENFVH PTGSSRSCSS YELQQQSMKR SNRRKYGRCH FWFTTKSWKP SSEQMDQDHS SSDSWNNNDA AASLENSASS DEEDIGSETR AIYSIVLKLP GHSTILNSTK LPSSDNLQVP EEELGMVDLE RKADKLQAQK SVDDGGSFPK SFSKLPIQLE SAVDTAKTSD VNSSVGKSTA TLPLSFKEAT LAKRFALKTR SQITKRKRMS LVKEKKAAQT
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Muscarinic acetylcholine receptor M3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Muscarinic acetylcholine receptor M3 Protein General Information | |
|---|---|
| Alternate Names | |
| PBS; EGBRS; HM3 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CHRM3 |
| Entrez Gene ID | 1131 |
| Ensemble Gene ID | ENSG00000133019 |
| RefSeq Protein Accession(s) | NP_000731.1 |
| RefSeq mRNA Accession(s) | NM_000740.3, NM_001347716.1, XM_005273032.3, XM_011544041.2, XM_011544043.2, XM_011544044.2, XM_011544046.2, XM_011544047.2, XM_017000152.1, XM_017000153.1, XM_017000154.1, XM_017000155.1, XM_017000156.1, XM_017000157.1, XM_017000158.1, XM_017000159.1, XM_017000160.1, XM_017000161.1, XM_017000162.1, XM_017000163.1 |
| UniProt ID(s) | P20309 |
| UniGene ID(s) | Hs.155736 |
| HGNC ID(s) | HGNC:1952 |
| COSMIC ID Link(s) | CHRM3 |
| KEGG Gene ID(s) | hsa:1131 |
| PharmGKB ID(s) | PA112 |
| General Description of Recombinant Human Muscarinic acetylcholine receptor M3 Protein. | |
| The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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