PDF DatasheetHuman Coagulation factor XIII A chain Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Coagulation factor XIII A chain based upon sequence from: Human
Host: QP9132 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Coagulation factor XIII A chain, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9132.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Gly39 – Met732
Amino Acid Sequence: GVNLQEFLNV TSVHLFKERW DTNKVDHHTD KYENNKLIVR RGQSFYVQID FSRPYDPRRD LFRVEYVIGR YPQENKGTYI PVPIVSELQS GKWGAKIVMR EDRSVRLSIQ SSPKCIVGKF RMYVAVWTPY GVLRTSRNPE TDTYILFNPW CEDDAVYLDN EKEREEYVLN DIGVIFYGEV NDIKTRSWSY GQFEDGILDT CLYVMDRAQM DLSGRGNPIK VSRVGSAMVN AKDDEGVLVG SWDNIYAYGV PPSAWTGSVD ILLEYRSSEN PVRYGQCWVF AGVFNTFLRC LGIPARIVTN YFSAHDNDAN LQMDIFLEED GNVNSKLTKD SVWNYHCWNE AWMTRPDLPV GFGGWQAVDS TPQENSDGMY RCGPASVQAI KHGHVCFQFD APFVFAEVNS DLIYITAKKD GTHVVENVDA THIGKLIVTK QIGGDGMMDI TDTYKFQEGQ EEERLALETA LMYGAKKPLN TEGVMKSRSN VDMDFEVENA VLGKDFKLSI TFRNNSHNRY TITAYLSANI TFYTGVPKAE FKKETFDVTL EPLSFKKEAV LIQAGEYMGQ LLEQASLHFF VTARINETRD VLAKQKSTVL TIPEIIIKVR GTQVVGSDMT VTVQFTNPLK ETLRNVWVHL DGPGVTRPMK KMFREIRPNS TVQWEEVCRP WVSGHRKLIA SMSSDSLRHV YGELDVQIQR RPSM
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Coagulation factor XIII A chain Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Coagulation factor XIII A chain Protein General Information | |
|---|---|
| Alternate Names | |
| F13A | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | F13A1 |
| Entrez Gene ID | 2162 |
| Ensemble Gene ID | ENSG00000124491 |
| RefSeq Protein Accession(s) | NP_000120.2 |
| RefSeq mRNA Accession(s) | NM_000129.3 |
| UniProt ID(s) | P00488 |
| UniGene ID(s) | Hs.335513 |
| HGNC ID(s) | HGNC:3531 |
| COSMIC ID Link(s) | F13A1 |
| KEGG Gene ID(s) | hsa:2162 |
| PharmGKB ID(s) | PA162 |
| General Description of Recombinant Human Coagulation factor XIII A chain Protein. | |
| Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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