PDF DatasheetHuman Galactocerebrosidase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Galactocerebrosidase based upon sequence from: Human
Host: QP9145 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Galactocerebrosidase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9145.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Tyr43 – Arg685
Amino Acid Sequence: YVLDDSDGLG REFDGIGAVS GGGATSRLLV NYPEPYRSQI LDYLFKPNFG ASLHILKVEI GGDGQTTDGT EPSHMHYALD ENYFRGYEWW LMKEAKKRNP NITLIGLPWS FPGWLGKGFD WPYVNLQLTA YYVVTWIVGA KRYHDLDIDY IGIWNERSYN ANYIKILRKM LNYQGLQRVK IIASDNLWES ISASMLLDAE LFKVVDVIGA HYPGTHSAKD AKLTGKKLWS SEDFSTLNSD MGAGCWGRIL NQNYINGYMT STIAWNLVAS YYEQLPYGRC GLMTAQEPWS GHYVVESPVW VSAHTTQFTQ PGWYYLKTVG HLEKGGSYVA LTDGLGNLTI IIETMSHKHS KCIRPFLPYF NVSQQFATFV LKGSFSEIPE LQVWYTKLGK TSERFLFKQL DSLWLLDSDG SFTLSLHEDE LFTLTTLTTG RKGSYPLPPK SQPFPSTYKD DFNVDYPFFS EAPNFADQTG VFEYFTNIED PGEHHFTLRQ VLNQRPITWA ADASNTISII GDYNWTNLTI KCDVYIETPD TGGVFIAGRV NKGGILIRSA RGIFFWIFAN GSYRVTGDLA GWIIYALGRV EVTAKKWYTL TLTIKGHFAS GMLNDKSLWT DIPVNFPKNG WAAIGTHSFE FAQFDNFLVE ATR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Galactocerebrosidase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Galactocerebrosidase Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | GALC |
| Entrez Gene ID | 2581 |
| Ensemble Gene ID | ENSG00000054983 |
| RefSeq Protein Accession(s) | NP_000144.2 |
| RefSeq mRNA Accession(s) | NM_000153.3, NM_001201401.1, NM_001201402.1 |
| UniProt ID(s) | P54803 |
| UniGene ID(s) | Hs.513439 |
| HGNC ID(s) | HGNC:4115 |
| COSMIC ID Link(s) | GALC |
| KEGG Gene ID(s) | hsa:2581 |
| PharmGKB ID(s) | PA28530 |
| General Description of Recombinant Human Galactocerebrosidase Protein. | |
| Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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