PDF DatasheetHuman Integrin alpha-V Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Integrin alpha-V based upon sequence from: Human
Host: QP9224 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Integrin alpha-V, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9224.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Asp891 – Thr1048
Amino Acid Sequence: DLALSEGDIH TLGCGVAQCL KIVCQVGRLD RGKSAILYVK SLLWTETFMN KENQNHSYSL KSSASFNVIE FPYKNLPIED ITNSTLVTTN VTWGIQPAPM PVPVWVIILA VLAGLLLLAV LVFVMYRMGF FKRVRPPQEE QEREQLQPHE NGEGNSET
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Integrin alpha-V Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Integrin alpha-V Protein General Information | |
|---|---|
| Alternate Names | |
| VTNR; MSK8; CD51; VNRA | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ITGAV |
| Entrez Gene ID | 3685 |
| Ensemble Gene ID | ENSG00000138448 |
| RefSeq Protein Accession(s) | NP_001138471.1 |
| RefSeq mRNA Accession(s) | NM_001144999.2, NM_001145000.2, NM_002210.4 |
| UniProt ID(s) | P06756 |
| UniGene ID(s) | Hs.436873 |
| HGNC ID(s) | HGNC:6150 |
| COSMIC ID Link(s) | ITGAV |
| KEGG Gene ID(s) | hsa:3685 |
| PharmGKB ID(s) | PA37336 |
| General Description of Recombinant Human Integrin alpha-V Protein. | |
| The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with Extracellular domain viral Tat protein ses to enhance angiogenesis in Kaposi’s sarcoma lesions. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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