PDF DatasheetHuman MBL-2 / MBL Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant MBL-2 / MBL based upon sequence from: Human
Host: QP9268 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) MBL-2 / MBL, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9268.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Glu21 – Ile248
Amino Acid Sequence: ETVTCEDAQK TCPAVIACSS PGINGFPGKD GRDGTKGEKG EPGQGLRGLQ GPPGKLGPPG NPGPSGSPGP KGQKGDPGKS PDGDSSLAAS ERKALQTEMA RIKKWLTFSL GKQVGNKFFL TNGEIMTFEK VKALCVKFQA SVATPRNAAE NGAIQNLIKE EAFLGITDEK TEGQFVDLTG NRLTYTNWNE GEPNNAGSDE DCVLLLKNGQ WNDVPCSTSH LAVCEFPI
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human MBL-2 / MBL Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human MBL-2 / MBL Protein General Information | |
|---|---|
| Alternate Names | |
| MBL-2; MBL; MBL2D; HSMBPC; MBP1; MBL; MBP; MBP-C; MBPD; COLEC1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MBL2 |
| Entrez Gene ID | 4153 |
| Ensemble Gene ID | ENSG00000165471 |
| RefSeq Protein Accession(s) | NP_000233.1 |
| RefSeq mRNA Accession(s) | NM_000242.2, XM_006717861.3, XM_011539816.2 |
| UniProt ID(s) | P11226 |
| UniGene ID(s) | Hs.499674 |
| HGNC ID(s) | HGNC:6922 |
| COSMIC ID Link(s) | MBL2 |
| KEGG Gene ID(s) | hsa:4153 |
| PharmGKB ID(s) | PA30665 |
| General Description of Recombinant Human MBL-2 / MBL Protein. | |
| Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complent pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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