PDF DatasheetRat NADPH oxidase 4 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant NADPH oxidase 4 based upon sequence from: Rat
Host: QP9309 protein expressed in Yeast.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Rattus norvegicus (Rat) NADPH oxidase 4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9309.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Gly210 – Glu424
Amino Acid Sequence: GGLLKYQTNL DTHPPGCISL NRTPSQNMSI ADYVSEHFHG SLPGGFSKLE DHYQKTLVKI CLEEPKFQAH FPQTWIWISG PLCLYCAERL YRCIRSNKPV TIISVINHPS DVMELRMIKE NFKARPGQYI ILHCPSVSAL ENHPFTLTMC PTETKATFGV HFKVVGDWTE RFRDLLLPPS SQDSEILPFI QSRNYPKLYI DGPFGSPFEE SLNYE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Rat NADPH oxidase 4 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Rat NADPH oxidase 4 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Nox4 |
| Entrez Gene ID | 85431 |
| Ensemble Gene ID | ENSRNOG00000013925 |
| RefSeq Protein Accession(s) | NP_445976.1 |
| RefSeq mRNA Accession(s) | NM_053524.1 |
| UniProt ID(s) | Q924V1 |
| UniGene ID(s) | Rn.14744 |
| COSMIC ID Link(s) | Nox4 |
| KEGG Gene ID(s) | rno:85431 |
| General Description of Recombinant Rat NADPH oxidase 4 Protein. | |
| Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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