PDF DatasheetHuman Pterin-4-alpha-carbinolamine dehydratase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Pterin-4-alpha-carbinolamine dehydratase based upon sequence from: Human
Host: QP9320 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Pterin-4-alpha-carbinolamine dehydratase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9320.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 – Thr104
Amino Acid Sequence: AGKAHRLSAE ERDQLLPNLR AVGWNELEGR DAIFKQFHFK DFNRAFGFMT RVALQAEKLD HHPEWFNVYN KVHITLSTHE CAGLSERDIN LASFIEQVAV SMT
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Pterin-4-alpha-carbinolamine dehydratase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Pterin-4-alpha-carbinolamine dehydratase Protein General Information | |
|---|---|
| Alternate Names | |
| PCD; PHS; DCOH; PCBD | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PCBD1 |
| Entrez Gene ID | 5092 |
| Ensemble Gene ID | ENSG00000166228 |
| RefSeq Protein Accession(s) | NP_000272.1 |
| RefSeq mRNA Accession(s) | NM_000281.3, NM_001289797.1 |
| UniProt ID(s) | P61457 |
| UniGene ID(s) | Hs.3192 |
| HGNC ID(s) | HGNC:8646 |
| COSMIC ID Link(s) | PCBD1 |
| KEGG Gene ID(s) | hsa:5092 |
| PharmGKB ID(s) | PA32985 |
| General Description of Recombinant Human Pterin-4-alpha-carbinolamine dehydratase Protein. | |
| Involved in tetrahydrobiopterin biosynthesis. Ses to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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