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Human CD133 / PROM1 / Prominin 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CD133 / PROM1 / Prominin 1 based upon sequence from: Human
Host: QP9348 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CD133 / PROM1 / Prominin 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9348.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Gly508 – Asn792
Amino Acid Sequence: GANVEKLICE PYTSKELFRV LDTPYLLNED WEYYLSGKLF NKSKMKLTFE QVYSDCKKNR GTYGTLHLQN SFNISEHLNI NEHTGSISSE LESLKVNLNI FLLGAAGRKN LQDFAACGID RMNYDSYLAQ TGKSPAGVNL LSFAYDLEAK ANSLPPGNLR NSLKRDAQTI KTIHQQRVLP IEQSLSTLYQ SVKILQRTGN GLLERVTRIL ASLDFAQNFI TNNTSSVIIE ETKKYGRTII GYFEHYLQWI EFSISEKVAS CKPVATALDT AVDVFLCSYI IDPLN
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human CD133 / PROM1 / Prominin 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CD133 / PROM1 / Prominin 1 Protein General Information | |
|---|---|
| Alternate Names | |
| CD133; PROM1; Prominin 1; Prom; CD133 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PROM1 |
| Entrez Gene ID | 8842 |
| Ensemble Gene ID | ENSG00000007062 |
| RefSeq Protein Accession(s) | NP_001139319.1 |
| RefSeq mRNA Accession(s) | NM_001145847.1, NM_001145848.1, NM_001145849.1, NM_001145850.1, NM_001145851.1, NM_001145852.1, NM_006017.2, XM_005248195.4, XM_005248196.4, XM_011513890.1, XM_011513892.2, XM_011513893.2, XM_011513894.2, XM_011513895.2, XM_011513896.2, XM_011513897.2, XM_011513899.2, XM_011513900.2, XM_011513902.2, XM_017008799.1, XM_017008802.1, XM_017008803.1, XM_017008804.1, XM_017008805.1 |
| UniProt ID(s) | O43490 |
| UniGene ID(s) | Hs.614734 |
| HGNC ID(s) | HGNC:9454 |
| COSMIC ID Link(s) | PROM1 |
| KEGG Gene ID(s) | hsa:8842 |
| PharmGKB ID(s) | PA33807 |
| General Description of Recombinant Human CD133 / PROM1 / Prominin 1 Protein. | |
| May play a role in cell differentiation, proliferation and apoptosis . Binds cholesterol in cholesterol-containing plasma mbrane microdomains and may play a role in the organization of the apical plasma mbrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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