PDF DatasheetHuman C1D Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant C1D based upon sequence from: Human
Host: QP938 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) C1D, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP938.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 – Asn135
Amino Acid Sequence: MAGEEINEDY PVEIHEYLSA FENSIGAVDE MLKTMMSVSR NELLQKLDPL EQAKVDLVSA YTLNSMFWVY LATQGVNPKE HPVKQELERI RVYMNRVKEI TDKKKAGKLD RGAASRFVKN ALWEPKSKNA SKVAN
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human C1D Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human C1D Protein General Information | |
|---|---|
| Alternate Names | |
| C1D, SUN-CoR, Rrp47, SUNCOR, LRP1, hC1D | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | C1D |
| Entrez Gene ID | 10438 |
| Ensemble Gene ID | ENSG00000197223 |
| RefSeq Protein Accession(s) | NP_001177192.1 |
| RefSeq mRNA Accession(s) | NM_001190263.1, NM_001190265.1, NM_006333.3, NM_173177.2 |
| UniProt ID(s) | Q13901 |
| UniGene ID(s) | Hs.602900 |
| HGNC ID(s) | HGNC:29911 |
| COSMIC ID Link(s) | C1D |
| KEGG Gene ID(s) | hsa:10438 |
| PharmGKB ID(s) | PA164717007 |
| General Description of Recombinant Human C1D Protein. | |
| Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3′-5′ end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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