PDF DatasheetHuman Semaphorin-7A Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Semaphorin-7A based upon sequence from: Human
Host: QP9385 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Semaphorin-7A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9385.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Gln45 – Ala648
Amino Acid Sequence: QGHLRSGPRI FAVWKGHVGQ DRVDFGQTEP HTVLFHEPGS SSVWVGGRGK VYLFDFPEGK NASVRTVNIG STKGSCLDKR DCENYITLLE RRSEGLLACG TNARHPSCWN LVNGTVVPLG EMRGYAPFSP DENSLVLFEG DEVYSTIRKQ EYNGKIPRFR RIRGESELYT SDTVMQNPQF IKATIVHQDQ AYDDKIYYFF REDNPDKNPE APLNVSRVAQ LCRGDQGGES SLSVSKWNTF LKAMLVCSDA ATNKNFNRLQ DVFLLPDPSG QWRDTRVYGV FSNPWNYSAV CVYSLGDIDK VFRTSSLKGY HSSLPNPRPG KCLPDQQPIP TETFQVADRH PEVAQRVEPM GPLKTPLFHS KYHYQKVAVH RMQASHGETF HVLYLTTDRG TIHKVVEPGE QEHSFAFNIM EIQPFRRAAA IQTMSLDAER RKLYVSSQWE VSQVPLDLCE VYGGGCHGCL MSRDPYCGWD QGRCISIYSS ERSVLQSINP AEPHKECPNP KPDKAPLQKV SLAPNSRYYL SCPMESRHAT YSWRHKENVE QSCEPGHQSP NCILFIENLT AQQYGHYFCE AQEGSYFREA QHWQLLPEDG IMAEHLLGHA CALA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Semaphorin-7A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Semaphorin-7A Protein General Information | |
|---|---|
| Alternate Names | |
| CDw108; H-Sema-L; CD108; H-SEMA-K1; SEMAK1; JMH; SEMAL | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SEMA7A |
| Entrez Gene ID | 8482 |
| Ensemble Gene ID | ENSG00000138623 |
| RefSeq Protein Accession(s) | NP_001139501.1 |
| RefSeq mRNA Accession(s) | NM_001146029.2, NM_001146030.2, NM_003612.4 |
| UniProt ID(s) | O75326 |
| UniGene ID(s) | Hs.24640 |
| HGNC ID(s) | HGNC:10741 |
| COSMIC ID Link(s) | SEMA7A |
| KEGG Gene ID(s) | hsa:8482 |
| PharmGKB ID(s) | PA35663 |
| General Description of Recombinant Human Semaphorin-7A Protein. | |
| Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.