PDF DatasheetHuman Toll-like receptor 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Toll-like receptor 1 based upon sequence from: Human
Host: QP9436 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Toll-like receptor 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9436.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ser25 – Thr580
Amino Acid Sequence: SEFLVDRSKN GLIHVPKDLS QKTTILNISQ NYISELWTSD ILSLSKLRIL IISHNRIQYL DISVFKFNQE LEYLDLSHNK LVKISCHPTV NLKHLDLSFN AFDALPICKE FGNMSQLKFL GLSTTHLEKS SVLPIAHLNI SKVLLVLGET YGEKEDPEGL QDFNTESLHI VFPTNKEFHF ILDVSVKTVA NLELSNIKCV LEDNKCSYFL SILAKLQTNP KLSNLTLNNI ETTWNSFIRI LQLVWHTTVW YFSISNVKLQ GQLDFRDFDY SGTSLKALSI HQVVSDVFGF PQSYIYEIFS NMNIKNFTVS GTRMVHMLCP SKISPFLHLD FSNNLLTDTV FENCGHLTEL ETLILQMNQL KELSKIAEMT TQMKSLQQLD ISQNSVSYDE KKGDCSWTKS LLSLNMSSNI LTDTIFRCLP PRIKVLDLHS NKIKSIPKQV VKLEALQELN VAFNSLTDLP GCGSFSSLSV LIIDHNSVSH PSADFFQSCQ KMRSIKAGDN PFQCTCELGE FVKNIDQVSS EVLEGWPDSY KCDYPESYRG TLLKDFHMSE LSCNIT
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Toll-like receptor 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Toll-like receptor 1 Protein General Information | |
|---|---|
| Alternate Names | |
| TIL; CD281; TIL. LPRS5; rsc786 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TLR1 |
| Entrez Gene ID | 7096 |
| Ensemble Gene ID | ENSG00000174125 |
| RefSeq Protein Accession(s) | NP_003254.2 |
| RefSeq mRNA Accession(s) | NM_003263.3, XM_005262662.4, XM_011513742.2, XM_011513743.2, XM_011513744.2, XM_011513745.2, XM_017008571.1, XM_017008572.1 |
| UniProt ID(s) | Q32MK4 |
| UniGene ID(s) | Hs.621817 |
| HGNC ID(s) | HGNC:11847 |
| COSMIC ID Link(s) | TLR1 |
| KEGG Gene ID(s) | hsa:7096 |
| PharmGKB ID(s) | PA36549 |
| General Description of Recombinant Human Toll-like receptor 1 Protein. | |
| Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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