PDF DatasheetHuman Toll-like receptor 8 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Toll-like receptor 8 based upon sequence from: Human
Host: QP9437 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Toll-like receptor 8, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9437.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Glu27 – Thr8
Amino Acid Sequence: EENFSRSYPC DEKKQNDSVI AECSNRRLQE VPQTVGKYVT ELDLSDNFIT HITNESFQGL QNLTKINLNH NPNVQHQNGN PGIQSNGLNI TDGAFLNLKN LRELLLEDNQ LPQIPSGLPE SLTELSLIQN NIYNITKEGI SRLINLKNLY LAWNCYFNKV CEKTNIEDGV FETLTNLELL SLSFNSLSHV PPKLPSSLRK LFLSNTQIKY ISEEDFKGLI NLTLLDLSGN CPRCFNAPFP CVPCDGGASI NIDRFAFQNL TQLRYLNLSS TSLRKINAAW FKNMPHLKVL DLEFNYLVGE IASGAFLTML PRLEILDLSF NYIKGSYPQH INISRNFSKL LSLRALHLRG YVFQELREDD FQPLMQLPNL STINLGINFI KQIDFKLFQN FSNLEIIYLS ENRISPLVKD TRQSYANSSS FQRHIRKRRS TDFEFDPHSN FYHFTRPLIK PQCAAYGKAL DLSLNSIFFI GPNQFENLPD IACLNLSANS NAQVLSGTEF SAIPHVKYLD LTNNRLDFDN ASALTELSDL EVLDLSYNSH YFRIAGVTHH LEFIQNFTNL KVLNLSHNNI YTLTDKYNLE SKSLVELVFS GNRLDILWND DDNRYISIFK GLKNLTRLDL SLNRLKHIPN EAFLNLPASL TELHINDNML KFFNWTLLQQ FPRLELLDLR GNKLLFLTDS LSDFTSSLRT LLLSHNRISH LPSGFLSEVS SLKHLDLSSN LLKTINKSAL ETKTTTKLSM LELHGNPFEC TCDIGDFRRW MDEHLNVKIP RLVDVICASP GDQRGKSIVS LELTTCVSDV T
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Toll-like receptor 8 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Toll-like receptor 8 Protein General Information | |
|---|---|
| Alternate Names | |
| CD288 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TLR8 |
| Entrez Gene ID | 51311 |
| Ensemble Gene ID | ENSG00000101916 |
| RefSeq Protein Accession(s) | NP_057694.2 |
| RefSeq mRNA Accession(s) | NM_016610.3, NM_138636.5, XM_011545529.1, XM_011545530.2 |
| UniProt ID(s) | Q9NR97 |
| UniGene ID(s) | Hs.660543 |
| HGNC ID(s) | HGNC:15632 |
| COSMIC ID Link(s) | TLR8 |
| KEGG Gene ID(s) | hsa:51311 |
| PharmGKB ID(s) | PA38009 |
| General Description of Recombinant Human Toll-like receptor 8 Protein. | |
| Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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