PDF DatasheetHuman Ficolin-2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Ficolin-2 based upon sequence from: Human
Host: QP9759 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Ficolin-2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9759.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Leu26 – Ala313
Amino Acid Sequence: LQAADTCPEV KMVGLEGSDK LTILRGCPGL PGAPGPKGEA GTNGKRGERG PPGPPGKAGP PGPNGAPGEP QPCLTGPRTC KDLLDRGHFL SGWHTIYLPD CRPLTVLCDM DTDGGGWTVF QRRVDGSVDF YRDWATYKQG FGSRLGEFWL GNDNIHALTA QGTSELRVDL VDFEDNYQFA KYRSFKVADE AEKYNLVLGA FVEGSAGDSL TFHNNQSFST KDQDNDLNTG NCAVMFQGAW WYKNCHVSNL NGRYLRGTHG SFANGINWKS GKGYNYSYKV SEMKVRPA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Ficolin-2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Ficolin-2 Protein General Information | |
|---|---|
| Alternate Names | |
| FCNL; EBP-37; P35; ficolin-2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | FCN2 |
| Entrez Gene ID | 2220 |
| Ensemble Gene ID | ENSG00000160339 |
| RefSeq Protein Accession(s) | NP_004099.2 |
| RefSeq mRNA Accession(s) | NM_004108.2, NM_015837.2 |
| UniProt ID(s) | Q15485 |
| UniGene ID(s) | Hs.54517 |
| HGNC ID(s) | HGNC:3624 |
| COSMIC ID Link(s) | FCN2 |
| KEGG Gene ID(s) | hsa:2220 |
| PharmGKB ID(s) | PA28070 |
| General Description of Recombinant Human Ficolin-2 Protein. | |
| May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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