PDF DatasheetHuman Erythroferrone Recombinant Protein Product Attributes
Product Type: Recombinant Protein. Sequence and Tag has been altered! See below.
Recombinant Erythroferrone based upon sequence from Human
Host: QP9790 protein expressed in Yeast.
Tag: N-terminal 6X-His (Formerly: His-SUMOstar(tm))
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Erythroferrone, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP9790.
Bioactivity Data: Untested
Full Length? Partial (Formerly: Full Length)
Expression Region: Pro195 – Val354 (Formerly: Full-length)
Amino Acid Sequence: PGPR APRVEAAFLC RLRRDALVER RALHELGVYY LPDAEGAFRR GPGLNLTSGQ YRAPVAGFYA LAATLHVALG EPPRRGPPRP RDHLRLLICI QSRCQRNASL EAIMGLESSS ELFTISVNGV LYLQMGQWTS VFLDNASGCS LTVRSGSHFS AVLLGV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Erythroferrone Protein:
Endotoxin Levels: Not determined.
Buffer: 20 mM Tris-HCl, 0.5 M NaCl, pH 8.0, 10% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Erythroferrone Protein General Information | |
|---|---|
| Alternate Names | |
| C1QTNF15; FAM132B; CTRP15 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | FAM132B |
| Entrez Gene ID | 151176 |
| Ensemble Gene ID | ENSG00000178752 |
| RefSeq Protein Accession(s) | NP_001278761.1 |
| RefSeq mRNA Accession(s) | NM_001291832.1 |
| UniProt ID(s) | Q4G0M1 |
| UniGene ID(s) | Hs.24951 |
| HGNC ID(s) | HGNC:26727 |
| KEGG Gene ID(s) | hsa:151176 |
| General Description of Recombinant Human Erythroferrone Protein. | |
| Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake (By similarity). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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