PDF DatasheetHuman Pyridoxal phosphate phosphatase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Pyridoxal phosphate phosphatase based upon sequence from: Human
Host: QP9859 protein expressed in Baculovirus, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Pyridoxal phosphate phosphatase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9859.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Met1 – Asp296
Amino Acid Sequence: MARCERLRGA ALRDVLGRAQ GVLFDCDGVL WNGERAVPGA PELLERLARA GKAALFVSNN SRRARPELAL RFARLGFGGL RAEQLFSSAL CAARLLRQRL PGPPDAPGAV FVLGGEGLRA ELRAAGLRLA GDPSAGDGAA PRVRAVLVGY DEHFSFAKLR EACAHLRDPE CLLVATDRDP WHPLSDGSRT PGTGSLAAAV ETASGRQALV VGKPSPYMFE CITENFSIDP ARTLMVGDRL ETDILFGHRC GMTTVLTLTG VSRLEEAQAY LAAGQHDLVP HYYVESIADL TEGLED
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Pyridoxal phosphate phosphatase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Pyridoxal phosphate phosphatase Protein General Information | |
|---|---|
| Alternate Names | |
| dJ37E16.5; CIN; PLP | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Pdxp |
| Entrez Gene ID | 57026 |
| Ensemble Gene ID | ENSG00000241360 |
| RefSeq Protein Accession(s) | NP_064711.1 |
| RefSeq mRNA Accession(s) | NM_020315.4 |
| UniProt ID(s) | Q96GD0 |
| UniGene ID(s) | Hs.632762 |
| HGNC ID(s) | HGNC:30259 |
| COSMIC ID Link(s) | Pdxp |
| KEGG Gene ID(s) | hsa:57026 |
| PharmGKB ID(s) | PA134882132 |
| General Description of Recombinant Human Pyridoxal phosphate phosphatase Protein. | |
| Protein serine phosphatase that dephosphorylates ‘Ser-3′ in cofilin and probably also dephosphorylates phospho-serine residues in DSTN. Regulates cofilin-dependent actin cytoskeleton reorganization. Required for normal progress through mitosis and normal cytokinesis. Does not dephosphorylate phospho-threonines in LIMK1. Does not dephosphorylate peptides containing phospho-tyrosine. Pyridoxal phosphate phosphatase. Has some activity towards pyridoxal 5′-phosphate (PLP), pyridoxine 5′-phosphate (PMP) and pyridoxine 5’-phosphate (PNP), with a highest activity with PLP followed by PNP.2 Publications. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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