PDF DatasheetHuman IL12RB2 / IL12R-beta 2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant IL12RB2 / IL12R-beta 2 based upon sequence from Human
Host: QP9881 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) IL12RB2 / IL12R-beta 2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP9881.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Lys24 – Asn622
Amino Acid Sequence: KIDACKRGDV TVKPSHVILL GSTVNITCSL KPRQGCFHYS RRNKLILYKF DRRINFHHGH SLNSQVTGLP LGTTLFVCKL ACINSDEIQI CGAEIFVGVA PEQPQNLSCI QKGEQGTVAC TWERGRDTHL YTEYTLQLSG PKNLTWQKQC KDIYCDYLDF GINLTPESPE SNFTAKVTAV NSLGSSSSLP STFTFLDIVR PLPPWDIRIK FQKASVSRCT LYWRDEGLVL LNRLRYRPSN SRLWNMVNVT KAKGRHDLLD LKPFTEYEFQ ISSKLHLYKG SWSDWSESLR AQTPEEEPTG MLDVWYMKRH IDYSRQQISL FWKNLSVSEA RGKILHYQVT LQELTGGKAM TQNITGHTSW TTVIPRTGNW AVAVSAANSK GSSLPTRINI MNLCEAGLLA PRQVSANSEG MDNILVTWQP PRKDPSAVQE YVVEWRELHP GGDTQVPLNW LRSRPYNVSA LISENIKSYI CYEIRVYALS GDQGGCSSIL GNSKHKAPLS GPHINAITEE KGSILISWNS IPVQEQMGCL LHYRIYWKER DSNSQPQLCE IPYRVSQNSH PINSLQPRVT YVLWMTALTA AGESSHGNER EFCLQGKAN
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human IL12RB2 / IL12R-beta 2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human IL12RB2 / IL12R-beta 2 Protein General Information | |
|---|---|
| Alternate Names | |
| IL12RB2; IL12R-beta 2; Ifnm; IL-12RB2; A930027I18Rik | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL12RB2 |
| Entrez Gene ID | 3595 |
| Ensemble Gene ID | ENSG00000081985 |
| RefSeq Protein Accession(s) | NP_001245143.1 |
| RefSeq mRNA Accession(s) | NM_001258214.1, NM_001258215.1, NM_001258216.1, NM_001319233.1, NM_001559.2, XM_005270825.2, XM_005270827.2, XM_005270828.3, XM_006710617.2, XM_011541383.2, XM_017001203.1 |
| UniProt ID(s) | Q99665 |
| UniGene ID(s) | Hs.479347 |
| HGNC ID(s) | HGNC:5972 |
| COSMIC ID Link(s) | IL12RB2 |
| KEGG Gene ID(s) | hsa:3595 |
| PharmGKB ID(s) | PA29787 |
| General Description of Recombinant Human IL12RB2 / IL12R-beta 2 Protein. | |
| Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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