PDF DatasheetMouse Nus1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Nus1 based upon sequence from Mouse
Host: QP9884 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Nus1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP9884.
Bioactivity Data: Untested
Full Length? Cytoplasmic Domain
Expression Region: Ser24 – Asp120
Amino Acid Sequence: SWLRVRFGTW NWIWRRCCRA ASAAVLAPLG FTLRKPRAVG RNRRHHRHPH GGPGPGPGPA ATHPRLRWRA DVRSLQKLPV HMGLLVTEEV QEPSFSD
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse Nus1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse Nus1 Protein General Information | |
|---|---|
| Alternate Names | |
| BC003223; D10Ertd438e; 1600027K07Rik; AU019165; AW538011; Dehydrodolichyl diphosphate synthase complex subunit Nu | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Nus1 |
| Entrez Gene ID | 52014 |
| Ensemble Gene ID | ENSMUSG00000023068 |
| RefSeq Protein Accession(s) | NP_084526.1 |
| RefSeq mRNA Accession(s) | NM_030250.2 |
| UniProt ID(s) | Q99LJ8 |
| UniGene ID(s) | Mm.199964 |
| COSMIC ID Link(s) | Nus1 |
| KEGG Gene ID(s) | mmu:52014 |
| General Description of Recombinant Mouse Nus1 Protein. | |
| With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precusrosor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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