PDF DatasheetHuman CNGA4 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CNGA4 based upon sequence from Human
Host: QP9966 protein expressed in Invitro-E.coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CNGA4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP9966.
Bioactivity Data: Untested
Full Length? Full Length Transmembrane Protein
Expression Region: Met1 – Glu575
Amino Acid Sequence: MSQDTKVKTT ESSPPAPSKA RKLLPVLDPS GDYYYWWLNT MVFPVMYNLI ILVCRACFPD LQHGYLVAWL VLDYTSDLLY LLDMVVRFHT GFLEQGILVV DKGRISSRYV RTWSFFLDLA SLMPTDVVYV RLGPHTPTLR LNRFLRAPRL FEAFDRTETR TAYPNAFRIA KLMLYIFVVI HWNSCLYFAL SRYLGFGRDA WVYPDPAQPG FERLRRQYLY SFYFSTLILT TVGDTPPPAR EEEYLFMVGD FLLAVMGFAT IMGSMSSVIY NMNTADAAFY PDHALVKKYM KLQHVNRKLE RRVIDWYQHL QINKKMTNEV AILQHLPERL RAEVAVSVHL STLSRVQIFQ NCEASLLEEL VLKLQPQTYS PGEYVCRKGD IGQEMYIIRE GQLAVVADDG ITQYAVLGAG LYFGEISIIN IKGNMSGNRR TANIKSLGYS DLFCLSKEDL REVLSEYPQA QTIMEEKGRE ILLKMNKLDV NAEAAEIALQ EATESRLRGL DQQLDDLQTK FARLLAELES SALKIAYRIE RLEWQTREWP MPEDLAEADD EGEPEEGTSK DEEGRASQEG PPGPE
Purity: Greater than 85% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human CNGA4 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CNGA4 Protein General Information | |
|---|---|
| Alternate Names | |
| OCNC2; OCNCb; OCNCBETA; CNCA2; CNG-4; CNG5; CNGB2; CNG4; Cyclic nucleotide-gated cation channel alpha | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CNGA4 |
| Entrez Gene ID | 1262 |
| Ensemble Gene ID | ENSG00000132259 |
| RefSeq Protein Accession(s) | NP_001032406.1 |
| RefSeq mRNA Accession(s) | NM_001037329.3 |
| UniProt ID(s) | Q8IV77 |
| UniGene ID(s) | Hs.434618 |
| HGNC ID(s) | HGNC:2152 |
| COSMIC ID Link(s) | CNGA4 |
| KEGG Gene ID(s) | hsa:1262 |
| General Description of Recombinant Human CNGA4 Protein. | |
| Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection (By similarity). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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