PDF DatasheetHuman Metalloendopeptidase OMA1, mitochondrial Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Metalloendopeptidase OMA1, mitochondrial based upon sequence from: Human
Host: QP9967 protein expressed in Invitro-E.coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Metalloendopeptidase OMA1, mitochondrial, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9967.
Bioactivity Data: Untested
Full Length? Full Length Transmembrane Protein
Amino Acid Sequence: HVFFRFNSLS NWRKCNTLAS TSRGCHQVQV NHIVNKYQGL GVNQCDRWSF LPGNFHFYST FNNKRTGGLS STKSKEIWRI TSKCTVWNDA FSRQLLIKEV TAVPSLSVLH PLSPASIRAI RNFHTSPRFQ AAPVPLLLMI LKPVQKLFAI IVGRGIRKWW QALPPNKKEV VKENIRKNKW KLFLGLSSFG LLFVVFYFTH LEVSPITGRS KLLLLGKEQF RLLSELEYEA WMEEFKNDML TEKDARYLAV KEVLCHLIEC NKDVPGISQI NWVIHVVDSP IINAFVLPNG QMFVFTGFLN SVTDIHQLSF LLGHEIAHAV LGHAAEKAGM VHLLDFLGMI FLTMIWAICP RDSLALLCQW IQSKLQEYMF NRPYSRKLEA EADKIGLLLA AKACADIRAS SVFWQQMEFV DSLHGQPKMP EWLSTHPSHG NRVEYLDRLI PQALKIREMC NCPPLSNPDP RLLFKLSTKH FLEESEKEDL NITKKQKMDT LPIQKQEQIP LTYIVEKRTG S
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Metalloendopeptidase OMA1, mitochondrial Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Metalloendopeptidase OMA1, mitochondrial Protein General Information | |
|---|---|
| Alternate Names | |
| 2010001O09Rik; YKR087C; ZMPOMA1; DAB1; MPRP-1; MPRP1; peptidase | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | OMA1 |
| Entrez Gene ID | 115209 |
| Ensemble Gene ID | ENSG00000162600 |
| RefSeq Protein Accession(s) | NP_660286.1 |
| RefSeq mRNA Accession(s) | NM_145243.4 |
| UniProt ID(s) | Q96E52 |
| UniGene ID(s) | Hs.425769 |
| HGNC ID(s) | HGNC:29661 |
| COSMIC ID Link(s) | OMA1 |
| KEGG Gene ID(s) | hsa:115209 |
| PharmGKB ID(s) | PA134911478 |
| General Description of Recombinant Human Metalloendopeptidase OMA1, mitochondrial Protein. | |
| Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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