PDF DatasheetHuman E3 ubiquitin-protein ligase MARCH2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant E3 ubiquitin-protein ligase MARCH2 based upon sequence from Human
Host: QP9968 protein expressed in Invitro-E.coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) E3 ubiquitin-protein ligase MARCH2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP9968.
Bioactivity Data: Untested
Full Length? Full Length Transmembrane Protein
Expression Region: Met1 – Val246
Amino Acid Sequence: MTTGDCCHLP GSLCDCSGSP AFSKVVEATG LGPPQYVAQV TSRDGRLLST VIRALDTPSD GPFCRICHEG ANGECLLSPC GCTGTLGAVH KSCLEKWLSS SNTSYCELCH TEFAVEKRPR PLTEWLKDPG PRTEKRTLCC DMVCFLFITP LAAISGWLCL RGAQDHLRLH SQLEAVGLIA LTIALFTIYV LWTLVSFRYH CQLYSEWRKT NQKVRLKIRE ADSPEGPQHS PLAAGLLKKV AEETPV
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human E3 ubiquitin-protein ligase MARCH2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human E3 ubiquitin-protein ligase MARCH2 Protein General Information | |
|---|---|
| Alternate Names | |
| MARCH-II; HSPC240; RNF172 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | 42796 |
| Entrez Gene ID | 51257 |
| Ensemble Gene ID | ENSG00000099785 |
| RefSeq Protein Accession(s) | NP_001005415.1 |
| RefSeq mRNA Accession(s) | NM_001005415.1, NM_001005416.1, NM_016496.4, XM_006722763.3, XM_017026853.1 |
| UniProt ID(s) | Q9P0N8 |
| UniGene ID(s) | Hs.631861 |
| HGNC ID(s) | HGNC:28038 |
| KEGG Gene ID(s) | hsa:51257 |
| PharmGKB ID(s) | PA134993565 |
| General Description of Recombinant Human E3 ubiquitin-protein ligase MARCH2 Protein. | |
| E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May be involved in endosomal trafficking through interaction with STX6. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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