PDF DatasheetRat Activin A / INHBA Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Activin A / INHBA based upon sequence from Rat
Host: QP5498 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5498.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 10 ng/mL in the Cytotoxicity of MPC-11 cells assay. The bioactivity acceptance criteria is set at 1 x 10^5 units/mg.
Monomer or Dimer: Dimer
Amino Acid Sequence: MGLECDGKVN ICCKKQFFVS FKDIGWNDWI IAPSGYHANY CEGECPSHIA GTSGSSLSFH STVINHYRMR GHSPFANLKS CCVPTKLRPM SMLYYDDGQN IIKKDIQNMI VEECGCS
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Rat Activin A / INHBA Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Rat Activin A / INHBA Protein General Information | |
|---|---|
| Alternate Names | |
| Activin A, INHBA Protein, EDF, FRP | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | INHBA |
| Entrez Gene ID | 29200 |
| Ensemble Gene ID | ENSRNOG00000014320 |
| RefSeq Protein Accession(s) | NP_058824.1 |
| RefSeq mRNA Accession(s) | NM_017128.2, XM_006254001.3, XM_008771712.2, XM_008771713.2, XM_008771714.2, XM_008771715.2, XM_008771716.2 |
| UniProt ID(s) | P18331 |
| UniGene ID(s) | Rn.9874 |
| COSMIC ID Link(s) | INHBA |
| KEGG Gene ID(s) | rno:29200 |
| General Description of Recombinant Rat Activin A / INHBA Protein. | |
| Activin A is a member of the transforming growth factor beta (TGF-?) family of proteins and functions to stimulate follicle-stimulating hormone (FSH) secretion. Activins are produced in many tissue types including the skin, gonads, lungs, and pituitary gland. Activins interact with receptor type I and type II serine/threonine protein kinases, to activate SMAD signaling and regulate diverse cellular functions, such as cell proliferation, differentiation, wound healing, apoptosis, and metabolism. Activin A is a homodimer comprised of two activin ?A chains. Cleavage of the N-terminal propeptide renders the activin protein biologically active. Rat Activin A shares 100% amino acid sequence identity with human, mouse, porcine, bovine, and feline activin A proteins. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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