Rat VEGFA-164 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant VEGFA-164 based upon sequence from: Rat
Host: QP5217 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5217.
Bioactivity Data: Rat VEGFA-164 bioactivity tested in HUVEC assay. Rat VEGFA-164 induces HUVEC proliferation (typical ED50 is ? 10 ng/ml)
Monomer or Dimer: Monomer
Amino Acid Sequence: MAPTTEGEQK AHEVVKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNVTMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKHCEPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Rat VEGFA-164 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
Recombinant Rat VEGFA-164 Protein General Information | |
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Alternate Names | |
VEGF, VEGFA, VEGF164, VEGF-A, VPF, Vegf | |
Curated Database and Bioinformatic Data | |
Gene Symbol | VEGFA |
RefSeq Protein Accession(s) | NP_001274037.1 |
RefSeq mRNA Accession(s) | NM_001287108.1 |
UniProt ID(s) | P16612-2 |
COSMIC ID Link(s) | VEGFA |
General Description of Recombinant Rat VEGFA-164 Protein . | |
Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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