PDF DatasheetHuman Anti-TLE1 (Synovial Sarcoma Marker) Antibody Product Attributes
Species: Human
Tested Applications: IHC.
Clonality: Monoclonal
Anti-TLE1 (Synovial Sarcoma Marker) Antibody Clone: TLE1/2085
Clone TLE1/2085 Host and Isotype: Mouse IgG2a, kappa
Anti-Human TLE1 (Synovial Sarcoma Marker) Positive Control Sample: HeLa, HepG2 or Jurkat cells. Endometrium Carcinoma or Sarcomas
Cellular Localization of Antibody TLE1/2085 Staining: Nuclear
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant fragment (aa 175-338) of human TLE1 (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.
TLE1 (Synovial Sarcoma Marker) Previously Observed Antibody Staining Patterns
| TLE1 (Synovial Sarcoma Marker) General Information | |
|---|---|
| Alternate Names | |
| Enhancer of split groucho 1 (ESG1); Enhancer of split groucho-like protein 1; GRG1; TLE1; Transducin like enhancer of split 1; Transducin-like enhancer protein 1 | |
| Molecular Weight | |
| 83kDa | |
| Chromosomal Location | |
| Ships on blue ice. | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | 7088 |
| Entrez Gene ID | TLE1 |
| UniProt ID(s) | Q04724 |
| UniGene ID(s) | Hs197320; 689805 |
| COSMIC ID Link(s) | TLE1 |
| KEGG Gene ID(s) | hsa:7088 |
| General Description of TLE1 (Synovial Sarcoma Marker). | |
| Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein 1 (TLE1) is a protein that is encoded by the TLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies. | |
Limitations and Warranty
enQuire Bio’s product, TLE1 (Synovial Sarcoma Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.
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