Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with CD29 Monoclonal Antibody (C29/1781).
Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with CD29 Monoclonal Antibody (C29/1781).Formalin-fixed, paraffin-embedded human Small Intestine stained with CD29 Monoclonal Antibody (C29/1781).

Anti-CD209 / DC-SIGN Antibody Clone C209/1781

$ 118.00$ 418.00
Please Select Product Options Below To View The Catalog Number.

SKU: 30835-MSM1
Species: Human
Tested Applications: Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG2b kappa
Mass Spec Validated?: Not MS Validated

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Datasheets and Documentation
Product Datasheet
SKU: 30835-MSM1-P0
CD209 / DC-SIGN General Information
Alternate Names
DC-SIGN, Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin, CD209, Cluster of Differentiation 209,
Molecular Weight
45kDa
Chromosomal Location
19p13
Curated Database and Bioinformatic Data
Gene SymbolCD209
Entrez Gene ID30835
Ensemble Gene IDENSG00000090659
RefSeq Protein Accession(s)NP_001138366, NP_001138368, NP_001138369, NP_001138365, XP_005272529, NP_001138367, NP_066978, NP_001138371
RefSeq mRNA Accession(s)NM_001144897, NM_001144899, XM_005272472, NM_001144894, NM_001144895 NM_001144893, NM_001144896, NR_026692, NM_021155
RefSeq Genomic Accession(s)NC_018930, NC_000019, NG_012167
UniProt ID(s)B2R907, X6RB12, Q9NNX6, M0R0P0, B4E2A8
UniGene ID(s)B2R907, X6RB12, Q9NNX6, M0R0P0, B4E2A8
HGNC ID(s)1641
Cosmic ID(s)CD209
KEGG Gene ID(s)hsa:30835
PharmGKB ID(s)PA26199
General Description of CD209 / DC-SIGN.
DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and enCanineenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.

Human Anti-CD209 / DC-SIGN Antibody Product Attributes

Species: Human
Tested Applications: Immunohistochemistry (IHC).
Clonality: Monoclonal
Anti-CD209 / DC-SIGN Antibody Clone: C209/1781
Clone C209/1781 Host and Isotype: Mouse IgG2b kappa
Anti-Human CD209 / DC-SIGN Positive Control Sample: THP-1 or HeLa Cells. Small Intestine, Uterus or Lymph Node.
Cellular Localization of Antibody Secreted and Cell Surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant human CD209 protein fragment
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

CD209 / DC-SIGN Previously Observed Antibody Staining Patterns

Observed Antibody Staining Data By Tissue Type:

Variations in CD209 / DC-SIGN antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. Low, but measureable presence of CD209 / DC-SIGN could be seen in. We were unable to detect CD209 / DC-SIGN in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.

Limitations and Warranty

enQuire Bio's CD209 / DC-SIGN Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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