Formalin-fixed, paraffin-embedded human Tonsil stained with CD27 Monoclonal Antibody (LPFS2/1611).
Formalin-fixed, paraffin-embedded human Tonsil stained with CD27 Monoclonal Antibody (LPFS2/1611).

Anti-CD27 Antibody Clone LPFS2/1611

$ 199.00$ 459.00
Please Select Product Options Below To View The Catalog Number.

SKU: 939-MSM2
Species: Human
Tested Applications: Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
939-MSM2-P0 Size: 20 ug, Tag: Unconjugated $ 199.00
939-MSM2-P1 Size: 100 ug, Tag: Unconjugated $ 429.00
939-MSM2-P2 Size: 200 ug, Tag: Unconjugated $ 459.00
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In Stock.
Flat Rate Shipping Anywhere in the US: $45
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SKU: 939-MSM2-P0
CD27 General Information
Alternate Names
CD27, TNFRSF7, TNFSF7
Molecular Weight
120kDa
Chromosomal Location
12p13
Curated Database and Bioinformatic Data
Gene SymbolCD27
Entrez Gene ID939
Ensemble Gene IDENSG00000139193
RefSeq Protein Accession(s)XP_011519344, NP_001233, XP_016875722, XP_016875721, XP_016875723
RefSeq mRNA Accession(s)XM_017020232, NM_001242, XM_017020233, XM_011521042, XM_017020234
RefSeq Genomic Accession(s)NC_000012, NG_031995, NC_018923
UniProt ID(s)P26842
UniGene ID(s)P26842
HGNC ID(s)11922
Cosmic ID(s)CD27
KEGG Gene ID(s)hsa:939
PharmGKB ID(s)PA162382107
General Description of CD27.
Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NF?B and SAPK/JNK and induces apoptosis.

Human Anti-CD27 Antibody Product Attributes

Species: Human
Tested Applications: Immunohistochemistry (IHC).
Clonality: Monoclonal
Anti-CD27 Antibody Clone: LPFS2/1611
Clone LPFS2/1611 Host and Isotype: Mouse IgG1
Anti-Human CD27 Positive Control Sample: Human peripheral blood lymphocytes. Human tonsil and lymph node.
Cellular Localization of Antibody Cell Surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant human CD22 protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

CD27 Previously Observed Antibody Staining Patterns

Observed Antibody Staining Data By Tissue Type:

Variations in CD27 antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. Low, but measureable presence of CD27 could be seen ingerminal center cells in the lymph node and tonsil and hematopoietic cells in the bone marrow. We were unable to detect CD27 in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.

Limitations and Warranty

enQuire Bio's CD27 Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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Anti-CD27 Antibody Clone LPFS2/1611

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