Antibody (Suitable for clinical applications)
Sample Type: FFPE Patient Samples.
Tested Applications: IHC. Approved for In Vitro Diagnostic Procedures on FFPE tissues. For tissue collection recommendations, please see datasheet sent with product.
Application Notes
| Specification | Recommendation |
|---|---|
| Recommended Dilution (Conc) | 1:25-1:75 |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation Parameters | 30 min at Room Temperature |
Prior to use, inspect vial for the presence of any precipitate or other unusual physical properties. These can indicate that the antibody has degraded and is no longer suitable for patient samples. Please run positive and negative controls simultaneously with all patient samples to account and control for errors in laboratory procedure. Use of methods or materials not recommended by enQuire Bio including change to dilution range and detection system should be routinely validated by the user.
Clonality: Monoclonal
Anti-CD56/Neural Cell Adhesion Molecule-1 Antibody Clone: 123C3.D5
Host and Isotype: Mouse IgG1, kappa
Recommended Positive Control Sample: Neuroblastoma
Cellular Localization of Antibody 123C3.D5 Staining: Cell membrane
Buffer and Stabilizer: PBS with 1% BSA and 0.05% NaN3
Antibody Concentration: Lot specific. Plese contact tech support for data.
Immunogen: BALB/C mice were injected with membrane preparation of a small cell lung carcinoma.
Storage Conditions: This antibody should be stored refrigerated (2-8°C). This product should not be used past the expiration date printed on the vial.
CD56/Neural Cell Adhesion Molecule-1 Information for Pathologists
| CD56/Neural Cell Adhesion Molecule-1 General Information | |
|---|---|
| Alternate Names | |
| Molecular Weight | |
| 94.6 kDa | |
| Chromosomal Location | |
| q23.2 [chr: 11] [chr_start: 112961247] [chr_end: 113278436] [strand: 1] | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | NCAM1 |
| Entrez Gene ID | 4684 |
| RefSeq Protein Accession(s) | NP_000606; NP_001229537; NP_001070150; NP_851996 |
| RefSeq mRNA Accession(s) | NM_001076682; NM_001242607; NM_001242608; NM_181351; NM_000615 |
| RefSeq Genomic Accession(s) | NC_000011; NG_032036 |
| UniProt ID(s) | P13591 |
| PharmGKB ID(s) | PA31459 |
| KEGG Gene ID(s) | hsa:4684 |
| General Description of CD56/Neural Cell Adhesion Molecule-1 . | |
| This antibody is specific to two proteins of 185 kDa and 145 kDa, identified as two isoforms of neural cell adhesion molecules (NCAM/CD56). NCAM is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytoma and neuroblastoma. | |
Limitations and Warranty
This antibody is manufactured in accordance with clinical good manufacturing practices in an ISO13485:2016 certified production facility. It is intended for multiple uses including in vitro diagnostic use and research use only applications. Please see vial label for expiration date. We strive to always deliver antibodies with a shelf life of at least two years.
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