Anti-EpCAM / CD326Antibody Validation Data
Analysis of Mass Spec data (dashed-line) of fractions stained with Ep-CAM / CD326 MS-QAVA™ monoclonal antibody [Clone: EGP40/1372] (solid-line), reveals that less than 5.2% of signal is attributable to non-specific binding of anti-Ep-CAM / CD326 [Clone: EGP40/1372] to targets other than TACSTD1 protein. Even frequently cited antibodies have much greater non-specific interactions, averaging over 30%. Data in image is from analysis in A431, RT4 and MCF7 cells.

Anti-EpCAM / CD326 Antibody Clone EGP40/1372

$ 118.00$ 418.00
Please Select Product Options Below To View The Catalog Number.

SKU: 4072-MSM12
Species: Human
Tested Applications: Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1
Mass Spec Validated?: MS-QAVA™ Validated

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Datasheets and Documentation
Product Datasheet
SKU: 4072-MSM12-P0
EpCAM / CD326 General Information
Alternate Names
EpCAM, Epithelial cell adhesion molecule, EGP40, CD326, Cluster of Differentiation 326
Molecular Weight
40-43kDa
Chromosomal Location
2p21
Curated Database and Bioinformatic Data
Gene SymbolTACSTD1
Entrez Gene ID4072
Ensemble Gene IDENSG00000119888
RefSeq Protein Accession(s)NP_002345
RefSeq mRNA Accession(s)NM_002354,
RefSeq Genomic Accession(s)NG_012352, NC_000002, NC_018913
UniProt ID(s)P16422
UniGene ID(s)P16422
HGNC ID(s)11529
Cosmic ID(s)EPCAM
KEGG Gene ID(s)hsa:4072
PharmGKB ID(s)PA35493
General Description of EpCAM / CD326.
EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (EpCAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

Human Anti-EpCAM / CD326 Antibody Product Attributes

Species: Human
Tested Applications: Immunohistochemistry (IHC). Additionally, this antibody has been validated by MS-QAVA™. Specificity has been quantitatively determined via Mass Spec.
Clonality: Monoclonal
Anti-EpCAM / CD326 Antibody Clone: EGP40/1372
Clone EGP40/1372 Host and Isotype: Mouse IgG1
Anti-Human EpCAM / CD326 Positive Control Sample: HT29 cells or Ovarian carcinoma
Cellular Localization of Antibody Cell surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant human EpCAM protein fragment from the extracellular domain (aa77-202)
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

EpCAM / CD326 Previously Observed Antibody Staining Patterns

Limitations and Warranty

This product is for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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