Formalin-fixed, paraffin-embedded Human Ovarian Carcinoma stained with LHCGR Monoclonal Antibody (LHCGR/1417).
Formalin-fixed, paraffin-embedded Human Ovarian Carcinoma stained with LHCGR Monoclonal Antibody (LHCGR/1417).

Anti-Luteinizing Hormone / LHCGR Antibody Clone LHCGR/1417

$ 118.00$ 418.00
Please Select Product Options Below To View The Catalog Number.

SKU: 3973-MSM3
Species: Human
Tested Applications: Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1 kappa
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
3973-MSM3-P0 Size: 20 ug, Tag: Unconjugated $ 118.00
3973-MSM3-P1 Size: 100 ug, Tag: Unconjugated $ 298.00
3973-MSM3-P2 Size: 200 ug, Tag: Unconjugated $ 418.00
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In Stock.
Flat Rate Shipping Anywhere in the US: $45
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SKU: 3973-MSM3-P0
Luteinizing Hormone / LHCGR General Information
Alternate Names
The luteinizing hormone / choriogonadotropin receptor, LHCGR, lutropin / choriogonadotropin receptor, LCGR, luteinizing hormone receptor, LHR,
Molecular Weight
78-85kDa
Chromosomal Location
2p21
Curated Database and Bioinformatic Data
Gene SymbolLHCGR
Entrez Gene ID3973
Ensemble Gene IDENSG00000138039
RefSeq Protein Accession(s)XP_006712078, XP_011531133, XP_016859579, XP_005264366, XP_011531136, XP_016859578, XP_011531130, NP_000224
RefSeq mRNA Accession(s)XM_011532828, XM_011532831, XM_017004090, XM_011532834, XM_006712015, XM_017004089, NM_000233
RefSeq Genomic Accession(s)NG_008193, NG_033050, NC_000002, NC_018913
UniProt ID(s)P22888
UniGene ID(s)P22888
HGNC ID(s)6585
Cosmic ID(s)LHCGR
KEGG Gene ID(s)hsa:3973
PharmGKB ID(s)PA30357
General Description of Luteinizing Hormone / LHCGR.
Recognizes a protein of 78-85kDa, which is identified as Luteinizing hormone / choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.

Human Anti-Luteinizing Hormone / LHCGR Antibody Product Attributes

Species: Human
Tested Applications: Immunohistochemistry (IHC).
Clonality: Monoclonal
Anti-Luteinizing Hormone / LHCGR Antibody Clone: LHCGR/1417
Clone LHCGR/1417 Host and Isotype: Mouse IgG1 kappa
Anti-Human Luteinizing Hormone / LHCGR Positive Control Sample: HepG2 or Jurkat cells. Ovarian Carcinoma
Cellular Localization of Antibody Cytoplasmic and Cell Surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant N-terminal fragment of human LHCGR
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

Luteinizing Hormone / LHCGR Previously Observed Antibody Staining Patterns

Observed Antibody Staining Data By Tissue Disease Status:

Tissues from cancer patients, for instance, have their own distinct pattern of Luteinizing Hormone / LHCGR expression as measured by anti-Luteinizing Hormone / LHCGR antibody immunohistochemical staining. The average level of expression by tumor is summarized in the table below. The variability row represents patient to patient variability in IHC staining.

Sample Type breast cancer carcinoid cervical cancer colorectal cancer endometrial cancer glioma head and neck cancer liver cancer lung cancer lymphoma melanoma ovarian cancer pancreatic cancer prostate cancer renal cancer skin cancer stomach cancer testicular cancer thyroid cancer urothelial cancer
Signal Intensity - ++ - - + - - + + - + - - + ++ + - + ++ +
LHCGR Variability ++ ++ ++ ++ ++ + ++ ++ ++ + ++ ++ ++ ++ ++ ++ + +++ ++ ++

Limitations and Warranty

enQuire Bio's Luteinizing Hormone / LHCGR Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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Anti-Luteinizing Hormone / LHCGR Antibody Clone LHCGR/1417

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