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Anti-Prolactin / PRL Antibody Clone PRL-Q8

$ 219.00
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SKU: QDX43
Species: Human
Tested Applications: ELISA, CLIA
Available Conjugates: Unconjugated
Isotype: Mouse IgG2b
Mass Spec Validated?: Not MS Validated

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Datasheets and Documentation
Product Datasheet
SKU: QDX43-100ug
Prolactin / PRL General Information
Alternate Names
Prolactin, Leuteotropic Hormone, Leuteotropin, PRL
Curated Database and Bioinformatic Data
Gene SymbolPRL
Entrez Gene ID5617
Ensemble Gene IDENSG00000172179
RefSeq Protein Accession(s)XP_011513056, NP_000939, XP_011513055, NP_001157030
RefSeq mRNA Accession(s)XM_011514753, NM_001163558, XM_011514754 NM_000948
RefSeq Genomic Accession(s)NC_000006, NG_029819, NC_018917
UniProt ID(s)Q5I0G2, P01236, Q5THQ0
UniGene ID(s)Q5I0G2, P01236, Q5THQ0
HGNC ID(s)9445
Cosmic ID(s)PRL
KEGG Gene ID(s)hsa:5617
PharmGKB ID(s)PA33790
General Description of Prolactin / PRL.
Prolactin (PRL), also known as luteotropic hormone or luteotropin, is an hormone formed by a 199aa mature chain consisting of three disulfide bonds. Prolactin is secreted from the pituitary gland in response to eating, mating, estrogen treatment, ovulation, and nursing. Prolactin is secreted in a pulsatile manner between these events. Prolactin also plays an essential role in metabolism, regulation of the immune system, and pancreatic development. In normal individuals,prolactin concentrations increase in response to physiologic stimuli such as sleep, stress, exercise, sexual intercourse, and hypoglycemia, and are also elevated during pregnancy, lactation, postpartum, and in the newborn infant. Though, prolactin levels are found elevated ven in non-pregnant and non-breastfeeding woman, or in male. The most common cause is a prolactinoma, a usually benign (not cancerous) prolactin-producing tumor of the pituitary gland. The prolactin test may be used as part of a work-up for irregular menstrual periods, fertility problems, some types of thyroid or adrenal gland dysfunction, anorexia, and polycystic ovarian syndrome. Prolactin tests were also used to diagnose, or monitor treatment of prolactinoma. Symptoms of a prolactinoma include headaches, vision problems (if tumor growth is causing pressure on an the optic nerve), and galactorrhea (milk production outside pregnancy or breastfeeding, or in a male).

Human Anti-Prolactin / PRL Antibody Product Attributes

Species: Human
Tested Applications: ELISA, CLIA.
Clonality: Monoclonal
Anti-Prolactin / PRL Antibody Clone: PRL-Q8
Clone PRL-Q8 Host and Isotype: Mouse IgG2b
Buffer and Stabilizer: PBS (pH 7.4)
Antibody Purification Method:Protein G
Storage Conditions: Upon receipt aliquot and store at -20C or -80C. Avoid repeated freeze.

Prolactin / PRL Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's Anti-Human Prolactin / PRL Antibody is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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