Anti-TAG-72 / CA72.4 Antibody Clone SPM536

$ 429.00
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SKU: 182875-MSM2X
Species: Human, Cow, Canine, and Rat
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1 kappa
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
182875-MSM2X-P1 Size: 100 ug, Tag: Unconjugated
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SKU: 182875-MSM2X-P1
TAG-72 / CA72.4 General Information
Alternate Names
CA 72.4, Tumor associated glycoprotein 72, anti-CA 72.4 antibody, anti-Tumor associated glycoprotein 72 antibody
Molecular Weight
Chromosomal Location
Not Known
Curated Database and Bioinformatic Data
Gene SymbolNot Known
Entrez Gene ID182875
Ensemble Gene IDWBGene00006447
RefSeq Protein Accession(s)NP_492674
RefSeq mRNA Accession(s)NM_060273
RefSeq Genomic Accession(s)NC_003279
UniProt ID(s)Q9XVS1
UniGene ID(s)Q9XVS1
Cosmic ID(s)tag-72
KEGG Gene ID(s)cel:CELE_C25A1.3
General Description of TAG-72 / CA72.4.
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity, 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma, adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72, anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

Human, Cow, Canine, and Rat Anti-TAG-72 / CA72.4 Antibody Product Attributes

Species: Human, Cow, Canine, and Rat
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC).
Application Notes: Flow Cytometry (0.5-1ug of antibody/million cells in 0.1ml), Immunofluorescence (1-2ug of antibody/ml), Immunohistochemistry (IHC) (Formalin-fixed) (0.5-1ug of antibody/ml for 30 minutes at RT)
Clonality: Monoclonal
Anti-TAG-72 / CA72.4 Antibody Clone: SPM536
Clone SPM536 Host and Isotype: Mouse IgG1 kappa
Anti-Human, Cow, Canine, and Rat TAG-72 / CA72.4 Positive Control Sample: Jurkat cells, Breast or lung carcinoma.
Cellular Localization of Antibody Cytoplasmic, cell surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Purified TAG-72 protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

TAG-72 / CA72.4 Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's TAG-72 / CA72.4 Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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Anti-TAG-72 / CA72.4 Antibody Clone SPM536 CA72.4 IHC human Colon Carcinoma (SPM536)-300x225.jpg