Western Blot of HepG2, PC3 and HeLa Cell Lysates with TIA1 Monoclonal Antibody (TIA1/1313).
Western Blot of HepG2, PC3 and HeLa Cell Lysates with TIA1 Monoclonal Antibody (TIA1/1313).

Anti-TIA1 Antibody Clone TIA1/1313

$ 199.00$ 459.00
Please Select Product Options Below To View The Catalog Number.

SKU: 7072-MSM1
Species: Human
Tested Applications: Western Blot
Available Conjugates: Unconjugated
Isotype: Mouse IgG2b
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
7072-MSM1-P0 Size: 20 ug, Tag: Unconjugated $ 199.00
7072-MSM1-P1 Size: 100 ug, Tag: Unconjugated $ 429.00
7072-MSM1-P2 Size: 200 ug, Tag: Unconjugated $ 459.00
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In Stock.
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
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SKU: 7072-MSM1-P0
TIA1 General Information
Alternate Names
TIA1
Molecular Weight
40kDa
Chromosomal Location
2p13
Curated Database and Bioinformatic Data
Gene SymbolTIA1
Entrez Gene ID7072
Ensemble Gene IDENSG00000116001
RefSeq Protein Accession(s)XP_016860279, NP_001338438, XP_011531383, XP_016860285, NP_001338449, NP_001338451, XP_016860288, NP_001338440, NP_071320, XP_005264585, XP_011531379, XP_011531384, XP_016860282, NP_001338439, NP_001338448, NP_001338450, XP_005264584, XP_016860280, NP_001338437, NP_001338443, NP_001338446, NP_071505, XP_016860284, NP_001338441, NP_001338442, NP_001338444, NP_001338454, XP_016860278, XP_016860283, XP_016860287, NP_001338445, NP_001338447, NP_001338452, NP_001338453, XP_005264588, XP_011531380, XP_016860281, XP_016860286
RefSeq mRNA Accession(s)XM_011533082, XM_017004789, XM_017004794, XM_017004796, NR_147217, NR_147220, NR_147221, NR_147227, NR_147229, XM_011533078, XM_017004793, XR_001738917, NM_001351511, NM_001351515, NM_001351524, NR_147231, XM_011533081, XM_017004795, XR_939715, NR_147224, XM_005264527, XM_017004790, NM_001351514, NM_001351519, NM_001351523, NM_022173, XM_017004791, XM_017004792, XM_017004799, NM_001351522, NR_147223, NR_147230, NM_001351508, NM_001351513, NM_001351518, NM_001351525, NR_147216, NR_147226, NR_147232, XM_011533077, XM_017004798, XR_244955, XR_939714 NM_001351510, NM_001351512, NR_147219, NR_147222, XM_005264528, XM_005264531, XM_017004797, XM_017004800, NM_001351509, NM_001351516, NM_001351517, NM_001351520, NM_001351521, NM_022037, NR_147218, NR_147225, NR_147228
RefSeq Genomic Accession(s)NG_029967, NC_018913, NC_000002
UniProt ID(s)F8W8I6, P31483
UniGene ID(s)F8W8I6, P31483
HGNC ID(s)11802
Cosmic ID(s)TIA1
KEGG Gene ID(s)hsa:7072
PharmGKB ID(s)PA36511
General Description of TIA1.
TIA-1 (T-cell intracytoplasmic antigen) is a cytoplasmic granule-associated protein, expressed in lymphocytes processing cytolytic potential. TIA-1 is a member of an RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15kDa protein thought to be derived from the carboxyl terminus of the 40kDa product by proteolytic processing. TIA1 antibody labels cytotoxic T cells and natural killer cells (NK cells). It is also expressed in T-cell lymphoma, large granular lymphocyte (LGL) leukemia and hairy cell leukemia. TIA1 expression in T-cell malignancies may help in differentiating LGL leukemia (high expression) from T-cell lymphocytosis and other T-cell diseases (low expression). TIA1 may also be used to label tumor-infiltrating lymphocytes in the study of immune response to malignancies.

Human Anti-TIA1 Antibody Product Attributes

Species: Human
Tested Applications: Western Blot.
Clonality: Monoclonal
Anti-TIA1 Antibody Clone: TIA1/1313
Clone TIA1/1313 Host and Isotype: Mouse IgG2b
Anti-Human TIA1 Positive Control Sample: HepG2, PC3 and HeLa cells. Tonsil.
Cellular Localization of Antibody Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant human TIA1 fragment of 102 amino acid residues (aa279-380)
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

TIA1 Previously Observed Antibody Staining Patterns

Observed Subcellular, Organelle Specific Staining Data:

Anti-TIA1 antibody staining is expected to be primarily localized to the cytosol and nucleoplasm.

Limitations and Warranty

enQuire Bio's TIA1 Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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Anti-TIA1 Antibody Clone TIA1/1313

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