Analysis of Protein Array containing more than 19,000 full-length human proteins using GPN1 Mouse Monoclonal Antibody (GPN1/2350) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.  A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
Analysis of Protein Array containing more than 19,000 full-length human proteins using GPN1 Mouse Monoclonal Antibody (GPN1/2350) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.  A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.SDS-PAGE Analysis Purified GPN1 Mouse Monoclonal Antibody (GPN1/2350).Confirmation of Purity and Integrity of Antibody.

GPN1 / XAB1 (DNA Repair & Protein Synthesis) Ultraspecific Antibody

Tested against >20,000 Human Proteins

$ 228.00$ 488.00
Please Select Product Options Below To View The Catalog Number.

SKU: 11321-MSM1
Species: Human
Tested Applications: ELISA, IHC
Available Conjugates: Unconjugated
Isotype: Mouse IgG1, kappa
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
11321-MSM1-P0 Size: 20 ug, Tag: Unconjugated $ 199.00
11321-MSM1-P1 Size: 100 ug, Tag: Unconjugated $ 429.00
11321-MSM1-P1ABX Size: 100 ug, Tag: Unconjugated $ 429.00
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SKU: 11321-MSM1-P0
GPN1 / XAB1 (DNA Repair & Protein Synthesis) General Information
Alternate Names
ATP(GTP) binding protein (ATPBD1A); GPN-loop GTPase 1; GPN1; MBD2-interacting protein (MBDin); NTPBP; RNA polymerase II associated protein 4 (RPAP4); XPA-binding protein 1 (XAB1) GTPase
Molecular Weight
42kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol11321
Entrez Gene IDGPN1
UniProt ID(s)Q9HCN4
UniGene ID(s)Hs18259
COSMIC ID Link(s)GPN1
KEGG Gene ID(s)hsa:11321
General Description of GPN1 / XAB1 (DNA Repair & Protein Synthesis).
GPN1 is involved in protein synthesis events. It is expressed ubiquitously with highest expression in testis. It binds to the RNA polymerase II- (Poll II) associated proteins RPAP1-3 and to XPA (a protein involved in DNA repair mechanisms), thereby forming an interface with Poll II. Via this interaction, GPN1 is thought to mediate the involvement of Pol II in both protein complex formation and protein chaperone/ scaffolding activities. In addition, GPN1 interacts with components of the integrator and molecular chaperone complexes, further implicating GPN1 in protein assembly. GPN1 contains a cluster of acidic amino acids in its C-terminal region and a series of sequences similar to those found in GTP-binding proteins in its N-terminal region, suggesting that GPN1 has possible GTPase activity.

Human Anti-GPN1 / XAB1 (DNA Repair & Protein Synthesis) Antibody Product Attributes

Species: Human
Tested Applications: ELISA, IHC.
Clonality: Monoclonal
Anti-GPN1 / XAB1 (DNA Repair & Protein Synthesis) Antibody Clone: GPN1/2350
Clone GPN1/2350 Host and Isotype: Mouse IgG1, kappa
Anti-Human GPN1 / XAB1 (DNA Repair & Protein Synthesis) Positive Control Sample: Pancreas, Testis, Thyroid or Bladder.
Cellular Localization of Antibody GPN1/2350 Staining: Cytoplasmic & Nuclear
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant full-length human GPN1 protein
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

GPN1 / XAB1 (DNA Repair & Protein Synthesis) Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's product, GPN1 / XAB1 (DNA Repair & Protein Synthesis) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

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Tested against >20,000 Human Proteins

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GPN1 / XAB1 (DNA Repair & Protein Synthesis) Ultraspecific Antibody

Tested against >20,000 Human Proteins

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