Analysis of Protein Array containing >19,000 full-length human proteins using CD123 Mouse Monoclonal Antibody (IL3RA/2065) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.  A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
Analysis of Protein Array containing >19,000 full-length human proteins using CD123 Mouse Monoclonal Antibody (IL3RA/2065) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.  A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

IL3RA / CD123 (Acute Myeloid Leukemia Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

$ 228.00$ 488.00
Please Select Product Options Below To View The Catalog Number.

SKU: 3563-MSM3
Species: Human
Tested Applications: ELISA
Available Conjugates: Unconjugated
Isotype: Mouse IgG2a, kappa
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
3563-MSM3-P0 Size: 20 ug, Tag: Unconjugated $ 199.00
3563-MSM3-P1 Size: 100 ug, Tag: Unconjugated $ 429.00
3563-MSM3-P1ABX Size: 100 ug, Tag: Unconjugated $ 429.00
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In Stock.
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
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SKU: 3563-MSM3-P0
IL3RA / CD123 (Acute Myeloid Leukemia Marker) General Information
Alternate Names
CD123; hIL3Ra; IL-3R-alpha; IL-3RA; IL3RAX; IL3RAY; IL3RX; IL3RY; Interleukin-3 Receptor, alpha; Interleukin3 receptor; Interleukin3 receptor, Y-chromosomal
Molecular Weight
~70kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol3563
Entrez Gene IDIL3RA
UniProt ID(s)P26951
UniGene ID(s)Hs632790
COSMIC ID Link(s)IL3RA
KEGG Gene ID(s)hsa:3563
General Description of IL3RA / CD123 (Acute Myeloid Leukemia Marker).
CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.

Human Anti-IL3RA / CD123 (Acute Myeloid Leukemia Marker) Antibody Product Attributes

Species: Human
Tested Applications: ELISA.
Clonality: Monoclonal
Anti-IL3RA / CD123 (Acute Myeloid Leukemia Marker) Antibody Clone: IL3RA/2065
Clone IL3RA/2065 Host and Isotype: Mouse IgG2a, kappa
Anti-Human IL3RA / CD123 (Acute Myeloid Leukemia Marker) Positive Control Sample: THP-1, RPMI-8226 or HDLM-2 cells. Tonsil, Lymph Node or Stomach
Cellular Localization of Antibody IL3RA/2065 Staining: Cell Surface and Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant human IL3RA protein fragment (apprx. aa 26-171) (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

IL3RA / CD123 (Acute Myeloid Leukemia Marker) Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's product, IL3RA / CD123 (Acute Myeloid Leukemia Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

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Tested against >20,000 Human Proteins

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IL3RA / CD123 (Acute Myeloid Leukemia Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

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