Formalin-fixed, paraffin-embedded human Lymph Node stained with PU.1 Mouse Monoclonal Antibody (PU1/2146).
Formalin-fixed, paraffin-embedded human Lymph Node stained with PU.1 Mouse Monoclonal Antibody (PU1/2146).Formalin-fixed, paraffin-embedded human Spleen stained with PU.1 Mouse Monoclonal Antibody (PU1/2146).Western Blot Analysis of THP-1 Cell Lysate using PU.1 Mouse Monoclonal Antibody (PU1/2146).Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with PU.1 Mouse Monoclonal Antibody (PU1/2146).

PU.1 (SPI-1) (B-Cell Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

$ 159.00$ 349.00
Please Select A Product To View The SKU.

SKU: 6688-MSM2
Species: Human
Tested Applications: WB, IHC
Available Conjugates: Unconjugated
Isotype: Mouse IgG2b, kappa
Mass Spec Validated?: Not MS Validated

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Shipping Information
In Stock: 1-2 Day Lead Time.
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: 6688-MSM2-P0
PU.1 (SPI-1) (B-Cell Marker) General Information
Alternate Names
Transcription Factor spi1; 31kDa Transforming Protein; Hematopoietic Transcription Factor PU.1; SFPI1; SPI1; SPIA; Spleen focus forming virus (SFFV) proviral integration oncogene spi1
Molecular Weight
40kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol6688
Entrez Gene IDSPI1
UniProt ID(s)P17947
UniGene ID(s)Hs502511
COSMIC ID Link(s)SPI1
KEGG Gene ID(s)hsa:6688
General Description of PU.1 (SPI-1) (B-Cell Marker).
PU.1 is a member of the ETS family of transcription factors and is important for normal B-cell development. It is expressed in the myeloid lineage and in immature as well as mature B-lymphocytes, with the exception of plasma cells. PU.1 is expressed in germinal center B-cells and mantle B-cells. Various lymphomas are also positive for this marker. It is essential during early B-cell differentiation. The absence of PU.1 results in total block of B-cell development at the pre-pro stage. PU.1 plays a key role in normal myeloid differentiation, and regulates the expression of immunoglobulin and other genes that are important for B-cell development.

Human Anti-PU.1 (SPI-1) (B-Cell Marker) Antibody Product Attributes

Species: Human
Tested Applications: WB, IHC.
Clonality: Monoclonal
Anti-PU.1 (SPI-1) (B-Cell Marker) Antibody Clone: PU1/2146
Clone PU1/2146 Host and Isotype: Mouse IgG2b, kappa
Anti-Human PU.1 (SPI-1) (B-Cell Marker) Positive Control Sample: K-562 Cells, THP-1 cells. Lymph Node, Spleen, Hodgkin s Lymphoma, Colon Carcinoma.
Cellular Localization of Antibody PU1/2146 Staining: Nuclear
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant fragment (apprx. aa 16-170) of human PU.1 protein (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

PU.1 (SPI-1) (B-Cell Marker) Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's product, PU.1 (SPI-1) (B-Cell Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

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Tested against >20,000 Human Proteins

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PU.1 (SPI-1) (B-Cell Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

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