Formalin-fixed, paraffin-embedded human Lymph Node stained with PU.1 Mouse Monoclonal Antibody (PU1/2146).
Formalin-fixed, paraffin-embedded human Lymph Node stained with PU.1 Mouse Monoclonal Antibody (PU1/2146).Formalin-fixed, paraffin-embedded human Spleen stained with PU.1 Mouse Monoclonal Antibody (PU1/2146).Western Blot Analysis of THP-1 Cell Lysate using PU.1 Mouse Monoclonal Antibody (PU1/2146).Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with PU.1 Mouse Monoclonal Antibody (PU1/2146).

PU.1 (SPI-1) (B-Cell Marker) MonoSpecific Antibody

$ 199.00$ 429.00
Please Select A Product To View The SKU.

SKU: 6688-MSM2
Species: Human
Tested Applications: WB, IHC
Available Conjugates: Unconjugated
Isotype: Mouse IgG2b, kappa
Mass Spec Validated?: Not MS Validated

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Datasheets and Documentation
Product Datasheet
SKU: 6688-MSM2-P0
PU.1 (SPI-1) (B-Cell Marker) General Information
Alternate Names
Transcription Factor spi1; 31kDa Transforming Protein; Hematopoietic Transcription Factor PU.1; SFPI1; SPI1; SPIA; Spleen focus forming virus (SFFV) proviral integration oncogene spi1
Molecular Weight
Chromosomal Location
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Curated Database and Bioinformatic Data
Gene Symbol6688
Entrez Gene IDSPI1
UniProt ID(s)P17947
UniGene ID(s)Hs502511
KEGG Gene ID(s)hsa:6688
General Description of PU.1 (SPI-1) (B-Cell Marker).
PU.1 is a member of the ETS family of transcription factors and is important for normal B-cell development. It is expressed in the myeloid lineage and in immature as well as mature B-lymphocytes, with the exception of plasma cells. PU.1 is expressed in germinal center B-cells and mantle B-cells. Various lymphomas are also positive for this marker. It is essential during early B-cell differentiation. The absence of PU.1 results in total block of B-cell development at the pre-pro stage. PU.1 plays a key role in normal myeloid differentiation, and regulates the expression of immunoglobulin and other genes that are important for B-cell development.

Human Anti-PU.1 (SPI-1) (B-Cell Marker) Antibody Product Attributes

Species: Human
Tested Applications: WB, IHC.
Clonality: Monoclonal
Anti-PU.1 (SPI-1) (B-Cell Marker) Antibody Clone: PU1/2146
Clone PU1/2146 Host and Isotype: Mouse IgG2b, kappa
Anti-Human PU.1 (SPI-1) (B-Cell Marker) Positive Control Sample: K-562 Cells, THP-1 cells. Lymph Node, Spleen, Hodgkin s Lymphoma, Colon Carcinoma.
Cellular Localization of Antibody PU1/2146 Staining: Nuclear
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant fragment (apprx. aa 16-170) of human PU.1 protein (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

PU.1 (SPI-1) (B-Cell Marker) Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's product, PU.1 (SPI-1) (B-Cell Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

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