Analysis of Protein Array containing more than 19,000 full-length human proteins using Superoxide Dismutase 1 Mouse Monoclonal Antibody (SOD1/2089).Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.  A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
Analysis of Protein Array containing more than 19,000 full-length human proteins using Superoxide Dismutase 1 Mouse Monoclonal Antibody (SOD1/2089).Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.  A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.SDS-PAGE Analysis Purified Superoxide Dismutase 1 Mouse Monoclonal Antibody (SOD1/2089).Confirmation of Integrity and Purity of Antibody.

Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) Ultraspecific Antibody

Tested against >20,000 Human Proteins

$ 158.00$ 348.00
Please Select Product Options Below To View The Catalog Number.

SKU: 6647-MSM1
Species: Human
Tested Applications: IHC
Available Conjugates: Unconjugated
Isotype: Mouse IgG
Mass Spec Validated?: Not MS Validated

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Datasheets and Documentation
Product Datasheet
SKU: 6647-MSM1-P0
Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) General Information
Alternate Names
Amyotrophic lateral sclerosis 1 (ALS1); Cu/Zn SOD; Cu/Zn Superoxide Dismutase; Epididymis Secretory Protein Li 44; Indophenoloxidase A (IPOA); Superoxide Dismutase [Cu-Zn]; Superoxide Dismutase 1 (SOD1)
Molecular Weight
23kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol6647
Entrez Gene IDSOD1
UniProt ID(s)P00441
UniGene ID(s)Hs443914
COSMIC ID Link(s)SOD1
KEGG Gene ID(s)hsa:6647
General Description of Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme).
Cu-Zn superoxide dismutase-1 (SOD-1) is a well-characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Enzymatically, SOD-1 facilitates the dismutation of oxygen radicals to hydrogen peroxide and also catalyzes pro-oxidant reactions, which include the peroxidase activity and hydroxyl radical generating activity. SOD-1 is ubiquitously expressed in somatic cells and functions as a homodimer. Defects in the gene encoding SOD-1 have been implicated in the progression of neurological diseases, including amyotrophic lateral sclerosis (ALS), a neurodegenerative disease characterized by the loss of spinal motor neurons, Down syndrome and Alzheimer s disease. In familial ALS, several mutations in SOD-1 predominate, resulting in the loss of zinc binding, the loss of scavenging activity of SOD-1, and correlate with an increase in neurotoxicity and motor neuron death.

Human Anti-Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) Antibody Product Attributes

Species: Human
Tested Applications: IHC.
Clonality: Monoclonal
Anti-Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) Antibody Clone: SOD1/2089
Clone SOD1/2089 Host and Isotype: Mouse IgG
Anti-Human Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) Positive Control Sample: HeLa or Jurkat Cells. Breast or Ovarian carcinoma
Cellular Localization of Antibody SOD1/2089 Staining: Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant full-length human SOD1 protein
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's product, Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

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Tested against >20,000 Human Proteins

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Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) Ultraspecific Antibody

Tested against >20,000 Human Proteins

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