Recombinant Human Pleiotrophin / PTN / HB-GAM Protein

$ 98.00$ 248.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10421
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 96% as determined by SDS­PAGE and HPLC.
Length (Amino Acids): 136

Product NumberDescriptionPrice
QP10421-ec-5ug Size: 5 ug, Tag: Untagged (Native Protein) $ 108.00
QP10421-ec-20ug Size: 20 ug, Tag: Untagged (Native Protein) $ 278.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP10421-ec-5ug
Recombinant Human Pleiotrophin / PTN / HB-GAM Protein General Information
Alternate Names
Pleiotrophin; PTN; HB-GAM; HBGF-8; NEGF1; HBNF; OSF-1; HB-GAM; HBGF8; HBNF-1; HARP; HBBM
Curated Database and Bioinformatic Data
Gene SymbolPTN
Entrez Gene ID5764
Ensemble Gene IDENSG00000105894
RefSeq Protein Accession(s)NP_001308315.1
RefSeq mRNA Accession(s)NM_001321386.2, NM_001321387.2, NM_002825.6
UniProt ID(s)P21246
UniGene ID(s)Hs.371249
HGNC ID(s)HGNC:9630
COSMIC ID Link(s)PTN
KEGG Gene ID(s)hsa:5764
PharmGKB ID(s)PA33974
General Description of Recombinant Human Pleiotrophin / PTN / HB-GAM Protein.
Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.

Human Pleiotrophin / PTN / HB-GAM Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant Pleiotrophin / PTN / HB-GAM based upon sequence from: Human
Host: QP10421 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human Pleiotrophin / PTN / HB-GAM, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10421.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity was measured by its ability to enhance neurite outgrowth of E16­E18 rat embryonic cortical neurons, when neurons were plated on 96 well culture plates that had been pre­coated with 100 ul/well of a solution of 5­10 ug/ml rHuPTN.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: GKKEKPEKKV KKSDCGEWQW SVCVPTSGDC GLGTREGTRT GAECKQTMKT QRCKIPCNWK KQFGAECKYQ FQAWGECDLN TALKTRTGSL KRALHNAECQ KTVTISKPCG KLTKPKPQAE SKKKKKEGKK QEKMLD
Purity: Greater than 96% as determined by SDS­PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human Pleiotrophin / PTN / HB-GAM Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 m filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Pleiotrophin / PTN / HB-GAM Protein

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