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Recombinant Human Leptin Protein

$ 98.00$ 248.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP1201
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: Untagged
Host: E. coli
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 146

Size
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Shipping Information
2-3 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP1201-ec-200ug
Recombinant Human Leptin Protein Protein General Information
Curated Database and Bioinformatic Data
Gene SymbolLEP
Entrez Gene ID3952
Ensemble Gene IDENSG00000174697
RefSeq Protein Accession(s)NP_000221.1
RefSeq mRNA Accession(s)NM_000230.2, XM_005250340.4
UniProt ID(s)P41159
UniGene ID(s)Hs.194236
HGNC ID(s)HGNC:6553
COSMIC ID Link(s)LEP
KEGG Gene ID(s)hsa:3952
PharmGKB ID(s)PA228
General Description of Recombinant Human Leptin Protein Protein.
May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.

Human Leptin Protein Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant Leptin Protein based upon sequence from Human
Host: QP1201 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human Leptin Protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP1201.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a chemotaxis bioassay using human Leptin R transfected BaF3 murine proB cells is less than 2 ng/ml, corresponding to a specific activity of > 5.0 × 105 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: VPIQKVQDDT KTLIKTIVTR INDISHTQSV SSKQKVTGLD FIPGLHPILT LSKMDQTLAV YQQILTSMPS RNVIQISNDL ENLRDLLHVL AFSKSCHLPW ASGLETLDSL GGVLEASGYS TEVVALSRLQ GSLQDMLWQL DLSPGC
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Human Leptin Protein Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Leptin Protein