DISC: Recombinant Human Activin A / INHBA Protein

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SKU: QP5357
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 117/234

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Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP5357-10ug

Recombinant Human Activin A / INHBA Protein General Information
Alternate Names
Activin A, INHBA Protein, EDF, FRP
Curated Database and Bioinformatic Data
Gene Symbol	INHBA
Entrez Gene ID	3624
Ensemble Gene ID	ENSG00000122641
RefSeq Protein Accession(s)	NP_002183.1
RefSeq mRNA Accession(s)	NM_002192.3, XM_017012176.1
UniProt ID(s)	P08476
UniGene ID(s)	Hs.28792
HGNC ID(s)	HGNC:6066
COSMIC ID Link(s)	INHBA
KEGG Gene ID(s)	hsa:3624
PharmGKB ID(s)	PA29877
General Description of Recombinant Human Activin A / INHBA Protein.
Activin A is a member of the transforming growth factor beta (TGF-?) family of proteins and functions to stimulate follicle-stimulating hormone (FSH) secretion. Activins are produced in many tissue types including the skin, gonads, lungs, and pituitary gland. Activins interact with receptor type I and type II serine/threonine protein kinases, to activate SMAD signaling and regulate diverse cellular functions, such as cell proliferation, differentiation, wound healing, apoptosis, and metabolism. Activin A is a homodimer comprised of two activin ?A chains. Cleavage of the N-terminal propeptide renders the activin protein biologically active. Human activin A shares 100% amino acid sequence identity with mouse, rat, porcine, bovine, and feline activin A proteins.

DISCONTINUED

Human Activin A / INHBA Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant Activin A / INHBA based upon sequence from: Human

Host: QP5357 protein expressed in E. coli.

Tag: Untagged

Recommended Applications: Bioactive

Application Notes: Please contact us for application specific information for QP5357.

Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 10 ng/mL in the Cytotoxicity of MPC-11 cells assay. The bioactivity acceptance criteria is set at 1 x 10^5 units/mg.

Monomer or Dimer: Dimer

Amino Acid Sequence: MGLECDGKVN ICCKKQFFVS FKDIGWNDWI IAPSGYHANY CEGECPSHIA GTSGSSLSFH STVINHYRMR GHSPFANLKS CCVPTKLRPM SMLYYDDGQN IIKKDIQNMI VEECGCS

Purity: Greater than 95% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Human Activin A / INHBA Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.

Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA

Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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