Recombinant Human G-CSF / CSF3 Protein

$ 79.00 – $ 3,948.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP5377
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 175

Product Number	Description	Price
QP5377-2ug	Size: 2 ug, Tag: Untagged (Native Protein)	$ 79.00
QP5377-10ug	Size: 10 ug, Tag: Untagged (Native Protein)	$ 189.00
QP5377-100ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 589.00
QP5377-500ug	Size: 500 ug, Tag: Untagged (Native Protein)	$ 2,408.00
QP5377-1mg	Size: 1 mg, Tag: Untagged (Native Protein)	$ 3,948.00

Shipping Information

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP5377-10ug

Recombinant Human G-CSF / CSF3 Protein (Animal Free) General Information
Alternate Names
G-CSF, CSF3, CSF3OS, C17orf33, GCSF
Curated Database and Bioinformatic Data
Gene Symbol	CSF3
Entrez Gene ID	1440
Ensemble Gene ID	ENSG00000108342
RefSeq Protein Accession(s)	NP_000750.1
RefSeq mRNA Accession(s)	NM_000759.3, NM_001178147.1, NM_172219.2, NM_172220.2
UniProt ID(s)	P09919
UniGene ID(s)	Hs.2233
HGNC ID(s)	HGNC:2438
COSMIC ID Link(s)	CSF3
KEGG Gene ID(s)	hsa:1440
PharmGKB ID(s)	PA26941
General Description of Recombinant Human G-CSF / CSF3 Protein (Animal Free).
Granulocyte-colony stimulating factor (G-CSF) is a cytokine that functions as a potent inducer of neutrophilic granulocyte proliferation, terminal differentiation, and activation. G-CSF synthesis occurs in monocyte, macrophage, epithelial, endothelial, and fibroblast cells after activation by bacterial endotoxins, tumor necrosis factor alpha (TNF?), interleukin 1 (IL-1), or interleukin 17 (IL-17). The functional activity of G-CSF is mediated through the granulocyte colony-stimulating factor receptor (G-CSF-R) to activate JAK/STAT and MAPK signal transduction pathways. G-CSF also promotes neurogenesis and inhibits neuronal apoptosis. Human and mouse G-CSF proteins are cross-reactive.

Human G-CSF / CSF3 Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant G-CSF / CSF3 based upon sequence from: Human

Host: QP5377 protein expressed in E. coli.

Tag: Untagged

Recommended Applications: Bioactive

Application Notes: Please contact us for application specific information for QP5377.

Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 50 pg/mL in the NFS-60 cell proliferation assay. The bioactivity acceptance criteria is set at 2 x 10^7 units/mg.

Monomer or Dimer: Monomer

Amino Acid Sequence: MTPLGPASSL PQSFLLKCLE QVRKIQGDGA ALQEKLCATY KLCHPEELVL LGHSLGIPWA PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL QALEGISPEL GPTLDTLQLD VADFATTIWQ QMEELGMAPA LQPTQGAMPA FASAFQRRAG GVLVASHLQS FLEVSYRVLR HLAQP

Purity: Greater than 95% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Human G-CSF / CSF3 Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.

Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA

Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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