Recombinant Human IL-1 alpha / IL1A / IL1F1 Protein

$ 69.00$ 3,600.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5298
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 159

Size
Tag Clear selection
Shipping Information
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP5298-10ug
Recombinant Human IL-1 alpha / IL1A / IL1F1 Protein General Information
Alternate Names
IL-1 alpha, IL1A, IL1F1 Protein, IL1, IL1-ALPHA, IL1F1, IL-1A
Curated Database and Bioinformatic Data
Gene Symbol IL1A
Entrez Gene ID 3552
Ensemble Gene ID ENSG00000115008
RefSeq Protein Accession(s) NP_000566.3
RefSeq mRNA Accession(s) NM_000575.4
UniProt ID(s) P01583
UniGene ID(s) Hs.1722
HGNC ID(s) HGNC:5991
COSMIC ID Link(s) IL1A
KEGG Gene ID(s) hsa:3552
PharmGKB ID(s) PA29807
General Description of Recombinant Human IL-1 alpha / IL1A / IL1F1 Protein .
Interleukin 1 alpha (IL-1?) is expressed by epithelial cells, activated macrophages, neutrophils, and endothelial cells to regulate immune responses. IL-1? signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MYD88) signaling pathway, which contains the cytoplasmic Toll/IL-1 receptor (TIR) domain adapter. IL-1? and the independently regulated IL-1? protein have overlapping proinflammatory activities to induce adhesion molecule expression on epithelial cells, control fever induction, initiate rheumatoid arthritis, and promote septic shock.

Human IL-1 alpha / IL1A / IL1F1 Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant IL-1 alpha / IL1A / IL1F1 based upon sequence from: Human
Host: QP5298 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5298.
Bioactivity Data: To pass QC, D10S cell proliferation must be significantly induced by less than 50 pg/ml or human IL-1 alpha / IL1A / IL1F1 (or activity must be at least 2.0 x 10^7 units/mg).
Monomer or Dimer: Monomer
Amino Acid Sequence: SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQA
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human IL-1 alpha / IL1A / IL1F1 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

There are no reviews yet.

Be the first to review “Recombinant Human IL-1 alpha / IL1A / IL1F1 Protein”

Your email address will not be published. Required fields are marked *

Share a Protocol (View Reviewed Protocols Below)

Protocol Title

Materials

Methods

Notes


  protocol submission gif

enQuire Bio, LLC   1825 Lawrence St, Ste 115   Denver, CO 80202
Phone: 1-855-344-1400 | enquire@enquirebio.com | Fax: 1-720-897-3730
Customer Service Available M-F 8AM-6PM MST or 24/7 Via Email

We consume cookies ensure that we give you the best experience on our website. If you continue to use this site we will assume that you are happy with it. Dismiss

Recombinant Human IL-1 alpha / IL1A / IL1F1 Protein

https://enquirebio.com/wp-content/uploads/2018/01/QP5298-Human-IL-1-alpha-IL1A-IL1F1-3-300x263.png