Recombinant Human IL-1 alpha / IL1A / IL1F1 Protein

$ 69.00$ 3,600.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5298
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 159

Product NumberDescriptionPrice
QP5298-500ug Size: 500 ug, Tag: Untagged (Native Protein) $ 2,350.00
QP5298-1mg Size: 1 mg, Tag: Untagged (Native Protein) $ 3,600.00
QP5298-2ug Size: 2 ug, Tag: Untagged (Native Protein) $ 69.00
QP5298-10ug Size: 10 ug, Tag: Untagged (Native Protein) $ 169.00
QP5298-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 639.00
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Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP5298-10ug
Recombinant Human IL-1 alpha / IL1A / IL1F1 Protein General Information
Alternate Names
IL-1 alpha, IL1A, IL1F1 Protein, IL1, IL1-ALPHA, IL1F1, IL-1A
Curated Database and Bioinformatic Data
Gene Symbol IL1A
Entrez Gene ID 3552
Ensemble Gene ID ENSG00000115008
RefSeq Protein Accession(s) NP_000566.3
RefSeq mRNA Accession(s) NM_000575.4
UniProt ID(s) P01583
UniGene ID(s) Hs.1722
HGNC ID(s) HGNC:5991
COSMIC ID Link(s) IL1A
KEGG Gene ID(s) hsa:3552
PharmGKB ID(s) PA29807
General Description of Recombinant Human IL-1 alpha / IL1A / IL1F1 Protein .
Interleukin 1 alpha (IL-1?) is expressed by epithelial cells, activated macrophages, neutrophils, and endothelial cells to regulate immune responses. IL-1? signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MYD88) signaling pathway, which contains the cytoplasmic Toll/IL-1 receptor (TIR) domain adapter. IL-1? and the independently regulated IL-1? protein have overlapping proinflammatory activities to induce adhesion molecule expression on epithelial cells, control fever induction, initiate rheumatoid arthritis, and promote septic shock.

Human IL-1 alpha / IL1A / IL1F1 Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant IL-1 alpha / IL1A / IL1F1 based upon sequence from: Human
Host: QP5298 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5298.
Bioactivity Data: To pass QC, D10S cell proliferation must be significantly induced by less than 50 pg/ml or human IL-1 alpha / IL1A / IL1F1 (or activity must be at least 2.0 x 10^7 units/mg).
Monomer or Dimer: Monomer
Amino Acid Sequence: SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQA
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human IL-1 alpha / IL1A / IL1F1 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human IL-1 alpha / IL1A / IL1F1 Protein

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