Recombinant Human IL-1 beta / IL1B Protein

$ 79.00 – $ 4,058.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP5291
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 154

Product Number	Description	Price
QP5291-2ug	Size: 2 ug, Tag: Untagged (Native Protein)	$ 79.00
QP5291-10ug	Size: 10 ug, Tag: Untagged (Native Protein)	$ 189.00
QP5291-100ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 529.00
QP5291-500ug	Size: 500 ug, Tag: Untagged (Native Protein)	$ 2,474.00
QP5291-1mg	Size: 1 mg, Tag: Untagged (Native Protein)	$ 4,058.00

Shipping Information

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP5291-10ug

Recombinant Human IL-1 beta / IL1B Protein (Animal Free) General Information
Alternate Names
IL-1 beta, IL1B, IL-1, IL1-BETA, IL1F2
Curated Database and Bioinformatic Data
Gene Symbol	IL1B
Entrez Gene ID	3553
Ensemble Gene ID	ENSG00000125538
RefSeq Protein Accession(s)	NP_000567.1
RefSeq mRNA Accession(s)	NM_000576.2
UniProt ID(s)	P01584
UniGene ID(s)	Hs.126256
HGNC ID(s)	HGNC:5992
COSMIC ID Link(s)	IL1B
KEGG Gene ID(s)	hsa:3553
PharmGKB ID(s)	PA29808
General Description of Recombinant Human IL-1 beta / IL1B Protein (Animal Free).
Interleukin 1 beta (IL-1?) is a pro-inflammatory cytokine that is produced by monocytes, macrophages, and dendritic cells (DCs). IL-1? signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MYD88) signaling pathway, which contains the cytoplasmic Toll/IL-1 receptor (TIR) domain adapter. IL-1? and the independently regulated IL-1? protein have overlapping proinflammatory activities to induce adhesion molecule expression on epithelial cells, control fever induction, initiate rheumatoid arthritis, and promote septic shock.

Human IL-1 beta / IL1B Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant IL-1 beta / IL1B based upon sequence from: Human

Host: QP5291 protein expressed in E. coli.

Tag: Untagged

Recommended Applications: Bioactive

Application Notes: Please contact us for application specific information for QP5291.

Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 12 pg/mL in the D10S cell proliferation assay. The bioactivity acceptance criteria is set at 8.3 x 10^7 units/mg.

Monomer or Dimer: Monomer

Amino Acid Sequence: MAPVRSLNCT LRDSQQKSLV MSGPYELKAL HLQGQDMEQQ VVFSMSFVQG EESNDKIPVA LGLKEKNLYL SCVLKDDKPT LQLESVDPKN YPKKKMEKRF VFNKIEINNK LEFESAQFPN WYISTSQAEN MPVFLGGTKG GQDITDFTMQ FVSS

Purity: Greater than 95% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Human IL-1 beta / IL1B Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.

Buffer: 10 mM sodium phosphate, pH 7.5

Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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