Recombinant Human IL-11 / interleukin 11 Protein

$ 69.00 – $ 4,898.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP5387
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 179

Product Number	Description	Price
QP5387-2ug	Size: 2 ug, Tag: Untagged (Native Protein)	$ 78.00
QP5387-10ug	Size: 10 ug, Tag: Untagged (Native Protein)	$ 188.00
QP5387-100ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 718.00
QP5387-500ug	Size: 500 ug, Tag: Untagged (Native Protein)	$ 3,338.00
QP5387-1mg	Size: 1 mg, Tag: Untagged (Native Protein)	$ 5,488.00

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Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP5387-10ug

Recombinant Human IL-11 / interleukin 11 Protein General Information
Alternate Names
IL-11, interleukin 11, AGIF, IL-11
Curated Database and Bioinformatic Data
Gene Symbol	IL11
Entrez Gene ID	3589
Ensemble Gene ID	ENSG00000095752
RefSeq Protein Accession(s)	NP_000632.1
RefSeq mRNA Accession(s)	NM_000641.3, NM_001267718.1
UniProt ID(s)	P20809
UniGene ID(s)	Hs.467304
HGNC ID(s)	HGNC:5966
COSMIC ID Link(s)	IL11
KEGG Gene ID(s)	hsa:3589
PharmGKB ID(s)	PA29781
General Description of Recombinant Human IL-11 / interleukin 11 Protein.
Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover. IL-11 binds the IL-11Ralpha (IL-11R?) receptor to activate JAK downstream signaling. Human IL-11 shows activity on murine cells.

Human IL-11 / interleukin 11 Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant IL-11 / interleukin 11 based upon sequence from: Human

Host: QP5387 protein expressed in E. coli.

Tag: Untagged

Recommended Applications: Bioactive

Application Notes: Please contact us for application specific information for QP5387.

Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 2.5 ng/mL in the T11 cell proliferation assay. The bioactivity acceptance criteria is set at 4 x 10^5 units/mg.

Monomer or Dimer: Monomer

Amino Acid Sequence: MPGPPPGPPR VSPDPRAELD STVLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK TLEPELGTLQ ARLDRLLRRL QLLMSRLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL

Purity: Greater than 95% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Human IL-11 / interleukin 11 Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.

Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA

Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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