Recombinant Human IL-15 Protein

$ 69.00$ 3,698.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP1153
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 115

Size
Tag Clear selection
Shipping Information
1-2 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP1153-2 ug
Recombinant Human IL-15 Protein General Information
Alternate Names
IL-15, IL15, Interleukin 15, IL-15
Curated Database and Bioinformatic Data
Gene SymbolIL15
Entrez Gene ID3600
Ensemble Gene IDENSG00000164136
RefSeq Protein Accession(s)NP_000576.1
RefSeq mRNA Accession(s)NM_000585.4, NM_172175.2
UniProt ID(s)P40933
UniGene ID(s)Hs.168132
HGNC ID(s)HGNC:5977
COSMIC ID Link(s)IL15
KEGG Gene ID(s)hsa:3600
PharmGKB ID(s)PA29790
General Description of Recombinant Human IL-15 Protein.
Interleukin 15 (IL-15) is a widely expressed proinflammatory cytokine that is structurally and functionally related to interleukin 2 (IL-2). IL-15 signals through JAK kinases to activate STAT3, STAT5, and STAT6 transcription factors. IL-15 regulates the activation of T cells, neutrophils, and macrophages, and is a stimulatory cytokine promoting dendritic cell function. IL-15 expression is dysregulated in chronic inflammatory disorders, including rheumatoid arthritis, psoriasis, and pulmonary inflammatory diseases. Therefore, IL-15 may serve as an effective therapeutic target, due to the beneficial outcomes of IL-15 neutralization in models of psoriasis and diabetes. Human IL-15 shows activity on mouse cells.

Human IL-15 Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant IL-15 based upon sequence from Human
Host: QP1153 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP1153.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 5 ng/mL in the CTLL-2 cell proliferation assay. The bioactivity acceptance criteria is set at 2 x 10^5 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISLESGDASI HDTVENLIIL ANNSLSSNGN VTESGCKECE ELEEKNIKEF LQSFVHIVQM FINTS
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Human IL-15 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium bicarbonate, pH 8.0
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

There are no reviews yet.

Be the first to review “Recombinant Human IL-15 Protein”

Your email address will not be published. Required fields are marked *

Share a Protocol (View Reviewed Protocols Below)

Protocol Title

Materials

Methods

Notes


  protocol submission gif

enQuire Bio, LLC   1825 Lawrence St, Ste 115   Denver, CO 80202
Phone: 1-855-344-1400 | enquire@enquirebio.com | Fax: 1-855-344-1400
Customer Service Available M-F 8AM-6PM MST or 24/7 Via Email
Scroll to top

We consume cookies ensure that we give you the best experience on our website. If you continue to use this site we will assume that you are happy with it. Dismiss

Recombinant Human IL-15 Proteinhttps://enquirebio.com/wp-content/uploads/2017/06/QP1153-Human-IL-15-300x194.png