Recombinant Human IL-15 Protein

$ 69.00$ 3,698.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP1153
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 115

Product NumberDescriptionPrice
QP1153-2 ug Size: 2 ug, Tag: Untagged (Native Protein) $ 69.00
QP1153-10 ug Size: 10 ug, Tag: Untagged (Native Protein) $ 169.00
QP1153-100 ug Size: 100 ug, Tag: Untagged (Native Protein) $ 479.00
QP1153-500 ug Size: 500 ug, Tag: Untagged (Native Protein) $ 2,258.00
QP1153-1 mg Size: 1 mg, Tag: Untagged (Native Protein) $ 3,698.00
Shipping Information
1-2 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP1153-2 ug
Recombinant Human IL-15 Protein General Information
Alternate Names
IL-15, IL15, Interleukin 15, IL-15
Curated Database and Bioinformatic Data
Gene SymbolIL15
Entrez Gene ID3600
Ensemble Gene IDENSG00000164136
RefSeq Protein Accession(s)NP_000576.1
RefSeq mRNA Accession(s)NM_000585.4, NM_172175.2
UniProt ID(s)P40933
UniGene ID(s)Hs.168132
HGNC ID(s)HGNC:5977
COSMIC ID Link(s)IL15
KEGG Gene ID(s)hsa:3600
PharmGKB ID(s)PA29790
General Description of Recombinant Human IL-15 Protein.
Interleukin 15 (IL-15) is a widely expressed proinflammatory cytokine that is structurally and functionally related to interleukin 2 (IL-2). IL-15 signals through JAK kinases to activate STAT3, STAT5, and STAT6 transcription factors. IL-15 regulates the activation of T cells, neutrophils, and macrophages, and is a stimulatory cytokine promoting dendritic cell function. IL-15 expression is dysregulated in chronic inflammatory disorders, including rheumatoid arthritis, psoriasis, and pulmonary inflammatory diseases. Therefore, IL-15 may serve as an effective therapeutic target, due to the beneficial outcomes of IL-15 neutralization in models of psoriasis and diabetes. Human IL-15 shows activity on mouse cells.

Human IL-15 Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant IL-15 based upon sequence from Human
Host: QP1153 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP1153.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 5 ng/mL in the CTLL-2 cell proliferation assay. The bioactivity acceptance criteria is set at 2 x 10^5 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISLESGDASI HDTVENLIIL ANNSLSSNGN VTESGCKECE ELEEKNIKEF LQSFVHIVQM FINTS
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Human IL-15 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium bicarbonate, pH 8.0
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human IL-15 Protein

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