Recombinant Human IL10 / Interleukin-10 Protein

$ 69.00 – $ 4,898.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP1151
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 161

Product Number	Description	Price
QP1151-2 ug	Size: 2 ug, Tag: Untagged (Native Protein)	$ 69.00
QP1151-10 ug	Size: 10 ug, Tag: Untagged (Native Protein)	$ 169.00
QP1151-100 ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 639.00
QP1151-500 ug	Size: 500 ug, Tag: Untagged (Native Protein)	$ 2,978.00
QP1151-1 mg	Size: 1 mg, Tag: Untagged (Native Protein)	$ 4,898.00

Shipping Information

1-2 days

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP1151-2 ug

Recombinant Human IL10 / Interleukin-10 Protein General Information
Alternate Names
IL10, Interleukin-10, IL10A, IL-10, TGIF, CSIF, GVHDS
Curated Database and Bioinformatic Data
Gene Symbol	IL10
Entrez Gene ID	3586
Ensemble Gene ID	ENSG00000136634
RefSeq Protein Accession(s)	NP_000563.1
RefSeq mRNA Accession(s)	NM_000572.2
UniProt ID(s)	P22301
UniGene ID(s)	Hs.193717
HGNC ID(s)	HGNC:5962
COSMIC ID Link(s)	IL10
KEGG Gene ID(s)	hsa:3586
PharmGKB ID(s)	PA29778
General Description of Recombinant Human IL10 / Interleukin-10 Protein.
Interleukin 10 (IL-10) is an anti-inflammatory cytokine produced by macrophages and type 2 T helper (Th2) cells. IL-10 inhibits the production of pro-inflammatory cytokines such as interferon gamma (IFNg), tumor necrosis factor alpha (TNF?), interleukin 2 (IL-2), interleukin 3 (IL-3), interleukin 4 (IL-4), and granulocyte-macrophage colony-stimulating factor (GM-CSF), made by macrophages and regulatory T cells. IL-10 also suppresses antigen presentation on antigen presenting cells, and enhances the survival, proliferation, and antibody production of B cells. Human IL-10 can act on murine cells, while murine IL-10 is not active on human cells.

Human IL10 / Interleukin-10 Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant IL10 / Interleukin-10 based upon sequence from Human

Host: QP1151 protein expressed in E. coli.

Tag: Untagged

Recommended Applications: Bioactive

Application Notes: Please contact us for application specific information for QP1151.

Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 5 ng/mL in the MC/9 cell Proliferation assay. The bioactivity acceptance criteria is set at 2 x 10^5 units/mg.

Monomer or Dimer: Monomer

Amino Acid Sequence: MSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR N

Purity: Greater than 95% as determined by SDS-PAGE.

Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.

Concentration of Human IL10 / Interleukin-10 Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.

Buffer: 10 mM sodium phosphate, pH 7.5

Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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