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Recombinant Human IL10 / Interleukin-10 Protein

$ 79.00$ 5,378.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5386
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 161

Product NumberDescriptionPrice
QP5386-2ug Size: 2 ug, Tag: Untagged (Native Protein) $ 79.00
QP5386-10ug Size: 10 ug, Tag: Untagged (Native Protein) $ 189.00
QP5386-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 699.00
QP5386-500ug Size: 500 ug, Tag: Untagged (Native Protein) $ 3,268.00
QP5386-1mg Size: 1 mg, Tag: Untagged (Native Protein) $ 5,378.00
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Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP5386-10ug
Recombinant Human IL10 / Interleukin-10 Protein (Animal Free) General Information
Alternate Names
IL10, Interleukin-10, IL10A, IL-10, TGIF, CSIF, GVHDS
Curated Database and Bioinformatic Data
Gene SymbolIL10
Entrez Gene ID3586
Ensemble Gene IDENSG00000136634
RefSeq Protein Accession(s)NP_000563.1
RefSeq mRNA Accession(s)NM_000572.2
UniProt ID(s)P22301
UniGene ID(s)Hs.193717
HGNC ID(s)HGNC:5962
COSMIC ID Link(s)IL10
KEGG Gene ID(s)hsa:3586
PharmGKB ID(s)PA29778
General Description of Recombinant Human IL10 / Interleukin-10 Protein (Animal Free).
Interleukin 10 (IL-10) is an anti-inflammatory cytokine produced by macrophages and type 2 T helper (Th2) cells. IL-10 inhibits the production of pro-inflammatory cytokines such as interferon gamma (IFNg), tumor necrosis factor alpha (TNFa), interleukin 2 (IL-2), interleukin 3 (IL-3), interleukin 4 (IL-4), and granulocyte-macrophage colony-stimulating factor (GM-CSF), made by macrophages and regulatory T cells. IL-10 also suppresses antigen presentation on antigen presenting cells, and enhances the survival, proliferation, and antibody production of B cells. Human IL-10 can act on murine cells, while murine IL-10 is not active on human cells.

Human IL10 / Interleukin-10 Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant IL10 / Interleukin-10 based upon sequence from: Human
Host: QP5386 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5386.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 5 ng/mL in the MC/9 cell Proliferation assay. The bioactivity acceptance criteria is set at 2 x 10^5 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR N
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human IL10 / Interleukin-10 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human IL10 / Interleukin-10 Protein