Proliferation of Human TF-1 cells at various concentrations of animal-free human LIF protein.

Recombinant Human LIF Protein

$ 88.00 – $ 3,188.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP5361
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 181

Product Number	Description	Price
QP5361-5ug	Size: 5 ug, Tag: Untagged (Native Protein)	$ 79.00
QP5361-25ug	Size: 25 ug, Tag: Untagged (Native Protein)	$ 189.00
QP5361-100ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 459.00
QP5361-500ug	Size: 500 ug, Tag: Untagged (Native Protein)	$ 1,748.00
QP5361-1mg	Size: 1 mg, Tag: Untagged (Native Protein)	$ 2,848.00

Shipping Information

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP5361-25ug

Recombinant Human LIF Protein General Information
Alternate Names
LIF, MLPLI, CDF, DIA, HILDA
Curated Database and Bioinformatic Data
Gene Symbol	LIF
Entrez Gene ID	3976
Ensemble Gene ID	ENSG00000128342
RefSeq Protein Accession(s)	NP_001244064.1
RefSeq mRNA Accession(s)	NM_001257135.1, NM_002309.4
UniProt ID(s)	P15018
UniGene ID(s)	Hs.2250
HGNC ID(s)	HGNC:6596
COSMIC ID Link(s)	LIF
KEGG Gene ID(s)	hsa:3976
PharmGKB ID(s)	PA30370
General Description of Recombinant Human LIF Protein.
Leukemia inhibitory factor (LIF) is a member of the interleukin 6 (IL-6) family that is made by a variety of adult and embryonic tissues. LIF signals through the glycoprotein 130 (gp130)/LIF receptor (LIFR) heterodimer to activate STAT3 and MAPK signaling. LIF functions during hematopoietic differentiation, neuronal cell differentiation, kidney development, and inflammatory processes. Human LIF may also be an important factor during human embryonic stem cell (hESC) self-renewal, pluripotency, and embryonic implantation.

Human LIF Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant LIF based upon sequence from: Human

Host: QP5361 protein expressed in E. coli.

Tag: Untagged

Recommended Applications: Bioactive

Application Notes: Please contact us for application specific information for QP5361.

Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 200 pg/mL in the TF-1 cell proliferation assay. The bioactivity acceptance criteria is set at 5 x 10^6 units/mg.

Monomer or Dimer: Monomer

Amino Acid Sequence: MSPLPITPVN ATCAIRHPCH NNLMNQIRSQ LAQLNGSANA LFILYYTAQG EPFPNNLDKL CGPNVTDFPP FHANGTEKAK LVELYRIVVY LGTSLGNITR DQKILNPSAL SLHSKLNATA DILRGLLSNV LCRLCSKYHV GHVDVTYGPD TSGKDVFQKK KLGCQLLGKY KQIIAVLAQA F

Purity: Greater than 95% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Human LIF Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.

Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA

Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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