Recombinant Human PDGF-B Protein

$ 169.00$ 3,598.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5307
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 110/220

Product NumberDescriptionPrice
QP5307-10ug Size: 10 ug, Tag: Untagged (Native Protein) $ 169.00
QP5307-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 469.00
QP5307-1mg Size: 1 mg, Tag: Untagged (Native Protein) $ 3,598.00
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Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP5307-100ug
Recombinant Human PDGF-B Protein General Information
Alternate Names
PDGF-B, IBGC5, PDGF2, SSV, PDGF-2, SIS, c-sis
Curated Database and Bioinformatic Data
Gene SymbolPDGFB
Entrez Gene ID5155
Ensemble Gene IDENSG00000100311
RefSeq Protein Accession(s)NP_002599.1
RefSeq mRNA Accession(s)NM_002608.3, NM_033016.3
UniProt ID(s)P01127
UniGene ID(s)Hs.1976
HGNC ID(s)HGNC:8800
COSMIC ID Link(s)PDGFB
KEGG Gene ID(s)hsa:5155
PharmGKB ID(s)PA33145
General Description of Recombinant Human PDGF-B Protein.
Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-a, TGF-b and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-a and PDGFR-b.

Human PDGF-B Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant PDGF-B based upon sequence from: Human
Host: QP5307 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5307.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 20 ng/mL in the BALB/c 3T3 cell proliferation assay. The bioactivity acceptance criteria is set at 5.0 x 10^4 units/mg.
Monomer or Dimer: Dimer
Amino Acid Sequence: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human PDGF-B Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human PDGF-B Protein

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