Recombinant Human PDGFA Protein

$ 79.00 – $ 3,948.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP5294
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 126/252

Product Number	Description	Price
QP5294-2ug	Size: 2 ug, Tag: Untagged (Native Protein)	$ 79.00
QP5294-10ug	Size: 10 ug, Tag: Untagged (Native Protein)	$ 189.00
QP5294-100ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 519.00
QP5294-1mg	Size: 500 ug, Tag: Untagged (Native Protein)	$ 2,408.00
QP5294-1mg	Size: 1 mg, Tag: Untagged (Native Protein)	$ 3,948.00

Shipping Information

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP5294-10ug

Recombinant Human PDGFA Protein (Animal Free) General Information
Alternate Names
PDGF1, PDGF-A
Curated Database and Bioinformatic Data
Gene Symbol	PDGFA
Entrez Gene ID	5154
Ensemble Gene ID	ENSG00000197461
RefSeq Protein Accession(s)	NP_002598.4
RefSeq mRNA Accession(s)	NM_002607.5, NM_033023.4
UniProt ID(s)	P04085
UniGene ID(s)	Hs.535898
HGNC ID(s)	HGNC:8799
COSMIC ID Link(s)	PDGFA
KEGG Gene ID(s)	hsa:5154
PharmGKB ID(s)	PA33144
General Description of Recombinant Human PDGFA Protein (Animal Free).
Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-a, TGF-b and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-a and PDGFR-b.

Human PDGFA Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant PDGFA based upon sequence from: Human

Host: QP5294 protein expressed in E. coli.

Tag: Untagged

Recommended Applications: Bioactive

Application Notes: Please contact us for application specific information for QP5294.

Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 50 ng/mL in the BALB/c 3T3 cell proliferation assay. The bioactivity acceptance criteria is set at 2.0 x 10^4 units/mg.

Monomer or Dimer: Dimer

Amino Acid Sequence: MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT

Purity: Greater than 95% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Human PDGFA Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.

Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA

Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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